Every year around 1000 Swedish infants are born more than two months prematurely. Preterm infants are at increased risk of damage to several important organs, including the brain, lungs, guts and eyes. Around 350 of these infants develop the eye disease retinopathy of prematurity (ROP) which, if left untreated, can threaten their sight.
Ten per cent, or around one hundred, of the preterm infants need the same treatment to prevent blindness.
"In the past 50 years it has been routine for all infants born very prematurely to be examined several times by ophthalmologists to identify children who need treatment for ROP, but this expensive method of screening can now perhaps be replaced by a considerably simpler and cheaper method, so that ophthalmological examination can be avoided in most cases," says Professor Ann Hellström of Sahlgrenska Academy.
The research team has previously identified another important link between preterm birth and vascular disease in the eye, the protein IGF-1, which is strongly linked to the infant's weight gain. Assisted by statisticians at the University of Gothenburg, the researchers have developed an assessment model known as WINROP (Weight IGF-1 Neonatal ROP), which is based on weekly measurements of the infant's weight and analyses of the serum levels of IGF-1. "However, one would prefer not to take any blood samples from the preterm infants, and therefore we wanted to investigate whether our surveillance model worked if we only used the infant's weight. We found that it works extremely well," says Professor Hellström.
In a review of medical records, information on the weekly weights of 350 infants was entered into the model, and the outcome was compared with the ophthalmological examinations performed on them.
"All infants at risk were on average identified a few months before the ophthalmologist had seen signs of ROP requiring treatment. The method could therefore not just save money but also make it possible for infants with eye problems to be identified earlier," says Professor Hellström.
The new WINROP model is now to be evaluated in a large British study and also on data from Brazilian and American infants. The material will be analysed during the summer of 2009.For further information, contact:
About 4000 undergraduate students and 1000 postgraduate students are enrolled at Sahlgrenska Academy. The staff is about 1500 persons. 850 of them are researchers and/or teachers.
University of Gothenburg, Sweden, has about 25 000 full-time students and a staff of 5 200. Its eight faculties offer training in the Creative Arts, Social Sciences, Natural Sciences, Humanities, Education, Information Technology, Business, Economics and Law, and Health Sciences.
Helena Aaberg | idw
A 'half-hearted' solution to one-sided heart failure
24.11.2017 | Boston Children's Hospital
New study points the way to therapy for rare cancer that targets the young
22.11.2017 | Rockefeller University
High-precision measurement of the g-factor eleven times more precise than before / Results indicate a strong similarity between protons and antiprotons
The magnetic moment of an individual proton is inconceivably small, but can still be quantified. The basis for undertaking this measurement was laid over ten...
Heat from the friction of rocks caused by tidal forces could be the “engine” for the hydrothermal activity on Saturn's moon Enceladus. This presupposes that...
The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.
Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....
The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...
Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.
That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...
15.11.2017 | Event News
15.11.2017 | Event News
30.10.2017 | Event News
24.11.2017 | Physics and Astronomy
24.11.2017 | Health and Medicine
24.11.2017 | Earth Sciences