Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Short-term radiation therapy successful on breast cancer

11.02.2010
McMaster researchers find cheaper therapy works better for women

An intense three-week course of radiation therapy is just as effective as the standard five-week regimen for women with early-stage breast cancer. Dr. Tim Whelan, a professor of oncology of the Michael G. DeGroote School of Medicine at McMaster University, led a team of researchers to find that women who received the accelerated therapy have a low risk of the breast cancer for as long as 12 years after treatment.

The results are to be published in the Feb. 11 issue of the New England Journal of Medicine (NEJM), and have been presented to a meeting of the American Society for Therapeutic Radiology and Oncology. The study concluded a shorter, more intense course of therapy is as safe and effective as the standard treatment for select women who have undergone breast-conserving surgery. Women who receive a three-week treatment – called accelerated hypofractionated whole-breast irradiation -- have a low risk of side effects and recurrence of the cancer more than decade after treatment.

It is just as effective as the standard five-week course of radiation following surgery to remove the malignancy. Dr. Whelan said the study's results will change cancer treatment practice not just in Canada, but throughout North America and around the world. "This is win-win: shorter intense treatment is better for the patient and less costly to provide," said Dr. Whelan, who is also a radiation oncologist at the Juravinski Cancer Centre at Hamilton Health Sciences. Many women with early-stage breast cancer are able to undergo breast-conserving therapy to keep their breast after treatment. Typically, this means they first have a lumpectomy to remove the cancer followed by a course of radiation therapy to kill any remaining cancer cells.

Between April 1993 and September 1996, researchers randomly assigned 1,234 women from Ontario and Quebec to be treated with either accelerated radiation or standard radiation. The participants were followed for 12 years to determine if the accelerated whole-breast radiation was as effective as the standard treatment. A decade after treatment, breast cancer returned in 6.2 percent of patients treated with the accelerated radiation therapy, compared to 6.7 percent for patients treated with standard therapy. Both groups of patients also had a good or excellent cosmetic outcome from the radiation treatments.

Whelan said further research is now looking at even shorter more intensive therapy. "We're now in the midst of further study on more intense radiation over an even shorter time, and we're seeing positive results."

Contact: Veronica McGuire Public Relations, Faculty of Health Sciences McMaster University Phone: 905-525-9140, ext. 22169 E-mail: vmcguir@mcmaster.ca

Veronica McGuire | EurekAlert!
Further information:
http://www.mcmaster.ca

More articles from Health and Medicine:

nachricht Nanoparticles as a Solution against Antibiotic Resistance?
15.12.2017 | Friedrich-Schiller-Universität Jena

nachricht Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First-of-its-kind chemical oscillator offers new level of molecular control

DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.

Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Engineers program tiny robots to move, think like insects

15.12.2017 | Power and Electrical Engineering

One in 5 materials chemistry papers may be wrong, study suggests

15.12.2017 | Materials Sciences

New antbird species discovered in Peru by LSU ornithologists

15.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>