Of those tested, 23 were determined to be infected and 94 were determined to be uninfected. When using the highest level of infection as the threshold for a positive test, the test was 86.4 percent sensitive for infection and 95.8 percent specific for esterase, and when using smallest level of detected infection as threshold, the test was found to be 59.9 percent sensitive and 98.8 percent specific, showing that testing for leukocyte esterase in the synovial fluid is a valuable addition to the diagnostic armamentarium for PJI. LE strips also aid in rapid testing. “While this is our first test of LE strips for use in diagnosing PJI, our findings show the test to be accurate for detecting infection in the synovial fluid. This is encouraging as we continue in our research to better understand, detect and treat PJI in our patients,” said Parvizi.Additional authors on the study include: Elie Ghanem, MD and Bahar Adeli, BA, both with the Rothman Institute at Jefferson.
Lee-Ann Landis | EurekAlert!
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