A Cleveland Clinic research team is developing virtual models of human knee joints to better understand how tissues and their individual cells react to heavy loads – virtual models that someday can be used to understand damage mechanisms caused by the aging process or debilitating diseases, such as osteoarthritis.
A macro-scale model of the knee (left) was created to study compressive loading of the joint. At the micro scale, the single-cell model (top, right) has been used in previous studies, while Erdemir’s 11-cell model better represents the effects of loading on the individual cells. (Erdemir/Cleveland Clinic)
Erdemir’s finite element model of the knee joint with representation of the cartilage, menisci and the associated bone structures. An enlarged model region (right) illustrates the mesh resolution of the simulation. (Erdemir/Cleveland Clinic)
The Department of Biomedical Engineering (BME) at the Lerner Research Institute is committed to investigation, innovation, and translation of scientific discoveries to enhance patient care. The Lerner Research Institute is home to Cleveland Clinic's laboratory-based, translational and clinical research. For more, visit www.lerner.ccf.org/bme.
Jamie Abel | EurekAlert!
Further reports about: > Biomedical > Ferchau Engineering > LRI > Lerner > OSC > Osteoarthritis > Supercomputer > aging process > body-level scales > cartilage > cartilage cells > chondrocytes > computing system > debilitating disease > debilitating diseases > human body > knee joint > musculoskeletal mechanics > single cell > state-of-the-art computational representations
A promising target for kidney fibrosis
21.04.2017 | Brigham and Women's Hospital
Stem cell transplants: activating signal paths may protect from graft-versus-host disease
20.04.2017 | Technische Universität München
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
20.04.2017 | Event News
18.04.2017 | Event News
03.04.2017 | Event News
25.04.2017 | Physics and Astronomy
25.04.2017 | Materials Sciences
25.04.2017 | Life Sciences