Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers identify potential new weapon in battle against HIV

12.01.2009
Researchers have discovered a potentially important new resistance factor in the battle against HIV infection: blood types.

An international team of researchers from Canadian Blood Services, Toronto’s Hospital for Sick Children (SickKids), and Lund University in Sweden have discovered that certain types of blood are more predisposed to contracting HIV, while others are more effective at fending it off.

A carbohydrate-containing molecule termed the Pk blood group, which is distinct from the well-known ABO and Rh blood grouping systems, is present at variable levels on the surface of white and red blood cells. A study to be published in the leading journal Blood, shows that cells from rare individuals who produce excess of this blood group have dramatically reduced sensitivity to HIV infection.

Conversely, another slightly more common subgroup of people who do not produce any Pk at all was found to be much more susceptible to the virus. Interestingly, Pk levels also vary substantially in the general population.

“This study is not suggesting that your blood type alone determines if you will get HIV,” said principal author Dr. Don Branch of Canadian Blood Services. “However, it does suggest that individuals who are exposed to the virus, may be helped or hindered by their blood type in fighting the infection.”

Increasing the level of the Pk blood group in cells in the laboratory also resulted in heightened resistance to HIV, while lowering it increased susceptibility. The Pk molecule has been previously studied extensively by Sick Kids’ Dr. Cliff Lingwood, and Lund University’s Dr. Martin Olsson has identified underlying genetic reasons for Pk blood group variation.

”This discovery implicates the Pk level as a new risk factor for HIV infection and demonstrates the importance of blood-group-related science”, says Dr. Olsson.

“The conclusions of this study pave the way for novel therapeutic approaches to induce HIV resistance and promote further understanding of the pandemic as a whole,” says Dr. Lingwood.

Ingela Bjoerck | alfa
Further information:
http://www.lu.se

More articles from Health and Medicine:

nachricht New vaccine production could improve flu shot accuracy
25.07.2017 | Duke University

nachricht Chances to treat childhood dementia
24.07.2017 | Julius-Maximilians-Universität Würzburg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Carbon Nanotubes Turn Electrical Current into Light-emitting Quasi-particles

Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers

Light-matter quasi-particles can be generated electrically in semiconducting carbon nanotubes. Material scientists and physicists from Heidelberg University...

Im Focus: Flexible proximity sensor creates smart surfaces

Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.

At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...

Im Focus: 3-D scanning with water

3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects

A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Closing the Sustainability Circle: Protection of Food with Biobased Materials

21.07.2017 | Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

The technology with a feel for feelings

12.07.2017 | Event News

 
Latest News

NASA mission surfs through waves in space to understand space weather

25.07.2017 | Physics and Astronomy

Strength of tectonic plates may explain shape of the Tibetan Plateau, study finds

25.07.2017 | Earth Sciences

The dense vessel network regulates formation of thrombocytes in the bone marrow

25.07.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>