Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers develop device to measure brain temperature non-invasively

03.05.2011
Non-invasive brain-temperature monitoring could be critical in life-saving cooling therapy

Doctors have long sought a way to directly measure the brain's temperature without inserting a probe through the skull. Now researchers have developed a way to get the brain's precise temperature with a device the diameter of a poker-chip that rests on a patient's head, according to findings presented May 1 at the annual meeting of the Pediatric Academic Societies in Denver.

"This is the first time that anyone has presented data on the brain temperature of a human obtained non-invasively," said principal researcher Dr, Thomas Bass, a neonatologist at Children's Hospital of The King's Daughters in Norfolk, Va., and a professor of pediatrics at the hospital's academic partner, Eastern Virginia Medical School.

The research also suggests that an injured brain can be significantly warmer than the body, a finding critical to cooling therapies that reduce brain damage in everyone from elderly heart attack victims to hypoxic newborns.

"Knowing the actual brain temperature may allow us to improve outcomes by keeping the brain at an optimum temperature," said Dr. Bass.

With the help of a $750,000 National Institutes of Health grant, a research team led by Dr. Bass adapted an instrument that calculates temperatures by detecting microwave emissions produced by all human tissue.

Those microwaves pass unimpeded through the skull, like light passing through a sheet of glass. As tissue temperatures increase, the emissions grow more intense. Engineers calibrated the device to measure the temperature of brain tissue 1.5 centimeters beneath the skull.

In the trial whose results were presented, the device was placed on the heads of infants undergoing cooling therapy at CHKD. The device's brain temperature readings were correlated with rectal and esophageal temperatures. The difference in temperature between the brain and the body recorded by other means was as high as 5.4% Fahrenheit.

"That's difference is larger than we expected," Dr. Bass said.

Dr. Bass, who pioneered research on cooling therapy for hypoxic newborns, and set about this research because he believed the therapy could be improved if doctors knew precise temperature of the damaged organ, the brain.

Hypoxic brain damage in infants occurs most often in full-term births when the child suffers oxygen loss either immediately before or during delivery. Because of a quirk in the brain, a child can be revived but brain cells continue to die over several days, resulting in brain damage or death. Doctors could do little to stop this progression; parents often watched helplessly as their sons and daughters literally died before their eyes.

Based on the observation that children rescued from freezing ponds after extended periods of time suffered little or no brain damage, cooling therapy involves chilling an infant's body to 92 degrees for 72 hours after brain injury.

A clinical trial on the therapy showed that cooling the child stops or reduces the progression of brain cell death, drastically reducing brain damage and death. The results were so positive that the therapy is now standard in advanced neonatal intensive-care units worldwide.

Cooling therapy is now used with other patients as well, including heart attack victims whose brains have suffered oxygen deprivation.

Because cooling therapy's success relies on the temperature of the brain, precise readings of the brain's temperature is likely to improve a therapy that's already proven remarkably effective.

Children's Hospital of The King's Daughters is the only freestanding pediatric hospital in Virginia.

Greg Raver-Lampman | EurekAlert!
Further information:
http://www.chkd.org/

More articles from Health and Medicine:

nachricht Organ-on-a-chip mimics heart's biomechanical properties
23.02.2017 | Vanderbilt University

nachricht Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Stingless bees have their nests protected by soldiers

24.02.2017 | Life Sciences

New risk factors for anxiety disorders

24.02.2017 | Life Sciences

MWC 2017: 5G Capital Berlin

24.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>