Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers develop a novel antibacterial orthodontic bracket cement

21.03.2014

Antibacterial orthodontic cement containing a quaternary ammonium monomer dimethylaminododecyl methacrylate

Today, at the 43rd Annual Meeting & Exhibition of the American Association for Dental Research (AADR), held in conjunction with the 38th Annual Meeting of the Canadian Association for Dental Research, Mary Anne Sampaio de Melo, from the University of Maryland, Baltimore, will present a research study titled "Antibacterial Orthodontic Cement Containing a Quaternary Ammonium Monomer Dimethylaminododecyl Methacrylate."

Demineralized lesions in enamel around orthodontic brackets are caused by acids from biofilm accumulation. The objectives of this study were to develop a novel antibacterial orthodontic bracket cement by incorporating a quaternary ammonium monomer dimethylaminododecyl methacrylate (DMADDM), and to investigate the effects on dental plaque microcosm biofilm response and enamel bond strength.

DMADDM with an alkyl chain length of 12 was synthesized and incorporated into the cement at mass fractions of 0%, 1.5% and 3%. Orthodontic cement Transbond XT served as control. Shear bond strength of metal brackets to human enamel was measured.

... more about:
»AADR »Ammonium »Cement »Dental »acid »antibacterial »lactic »metabolic

Cement remnant index scores were determined after bracket failure. A plaque microcosm biofilm model with human saliva as inoculum was used to measure metabolic activity, lactic acid production, and colony-forming units (CFU) for biofilms on orthodontic cements.

Incorporating DMADDM into orthodontic cement did not affect the shear bond strength (13.1 to 14.6 MPa; p = 0.09). Dental plaque microcosm biofilm viability was substantially inhibited when in contact with cement disks containing DMADDM. The new orthodontic adhesive reduced biofilm metabolic activity by up to 66% and lactic acid by 78% (p < 0.05). Biofilm total micro-organisms were reduced by up to 88%, total streptococci by 96%, and mutans streptococci by 98% (p < 0.05).

Increasing DMADDM mass fraction increased the antibacterial potency. Orthodontic cement containing 3% DMADDM was the most strongly antibacterial. These results show that the DMADDM-containing orthodontic cement inhibited biofilms and lactic acid without compromising the enamel bond strength, and hence may be promising to reduce or eliminate demineralization in enamel around orthodontic brackets.

###

This is a summary of abstract #1327, "Antibacterial Orthodontic Cement Containing a Quaternary Ammonium Monomer Dimethylaminododecyl Methacrylate," to be presented by Mary Anne Sampaio de Melo, Saturday, March 22, 2014, from 8 a.m. – 9:30 a.m. at the Charlotte Convention Center, room 213BC.

About the American Association for Dental Research

The American Association for Dental Research (AADR), headquartered in Alexandria, Va., is a nonprofit organization with more than 3,600 members in the United States. Its mission is: (1) to advance research and increase knowledge for the improvement of oral health; (2) to support and represent the oral health research community; and (3) to facilitate the communication and application of research findings. AADR is the largest Division of the International Association for Dental Research (IADR). To learn more about the AADR, visit http://www.aadr.org

Ingrid L. Thomas | EurekAlert!

Further reports about: AADR Ammonium Cement Dental acid antibacterial lactic metabolic

More articles from Health and Medicine:

nachricht Discovery points to a new path toward a universal flu vaccine
03.07.2015 | Rockefeller University

nachricht "CCS Telehealth Ostsachsen", Germany's largest telemedicine project, goes online in Dresden
02.07.2015 | Universitätsklinikum Carl Gustav Carus Dresden

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Viaducts with wind turbines, the new renewable energy source

Wind turbines could be installed under some of the biggest bridges on the road network to produce electricity. So it is confirmed by calculations carried out by a European researchers team, that have taken a viaduct in the Canary Islands as a reference. This concept could be applied in heavily built-up territories or natural areas with new constructions limitations.

The Juncal Viaduct, in Gran Canaria, has served as a reference for Spanish and British researchers to verify that the wind blowing between the pillars on this...

Im Focus: X-rays and electrons join forces to map catalytic reactions in real-time

New technique combines electron microscopy and synchrotron X-rays to track chemical reactions under real operating conditions

A new technique pioneered at the U.S. Department of Energy's Brookhaven National Laboratory reveals atomic-scale changes during catalytic reactions in real...

Im Focus: Iron: A biological element?

Think of an object made of iron: An I-beam, a car frame, a nail. Now imagine that half of the iron in that object owes its existence to bacteria living two and a half billion years ago.

Think of an object made of iron: An I-beam, a car frame, a nail. Now imagine that half of the iron in that object owes its existence to bacteria living two and...

Im Focus: Thousands of Droplets for Diagnostics

Researchers develop new method enabling DNA molecules to be counted in just 30 minutes

A team of scientists including PhD student Friedrich Schuler from the Laboratory of MEMS Applications at the Department of Microsystems Engineering (IMTEK) of...

Im Focus: Bionic eye clinical trial results show long-term safety, efficacy vision-restoring implant

Patients using Argus II experienced significant improvement in visual function and quality of life

The three-year clinical trial results of the retinal implant popularly known as the "bionic eye," have proven the long-term efficacy, safety and reliability of...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

World Conference on Regenerative Medicine in Leipzig: Last chance to submit abstracts until 2 July

25.06.2015 | Event News

World Conference on Regenerative Medicine: Abstract Submission has been extended to 24 June

16.06.2015 | Event News

MUSE hosting Europe’s largest science communication conference

11.06.2015 | Event News

 
Latest News

Siemens receives order for offshore wind power plant in Great Britain

03.07.2015 | Press release

'Déjà vu all over again:' Research shows 'mulch fungus' causes turfgrass disease

03.07.2015 | Agricultural and Forestry Science

Discovery points to a new path toward a universal flu vaccine

03.07.2015 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>