People with memory problems are less at risk of developing dementia than previously thought, a new study led by the University of Leicester and Nottinghamshire Healthcare NHS Trust reveals.
The five year research published in Acta Psychiatrica Scandinavica analysed data from 41 studies and dovetails with a Government focus to establish memory clinics in every town in the UK.
The research led by Dr Alex Mitchell from the University of Leicester Department of Cancer Studies and Molecular Medicine was carried out with Dr. Shiri-Feshki of Nottinghamshire Healthcare NHS Trust.
Dr Mitchell said: "This new research suggests that people with mild cognitive impairment (MCI) appear to have a lower risk of progressing to dementia than previously believed.
"Mild cognitive impairment (MCI) is an important disorder of memory and related areas found in about 1 in 6 people seen in general practice. The condition can occur in mid or late life and until recently most doctors told people with MCI that their risk of developing dementia was up to 15% per year making deterioration almost inevitable within 5 to 10 years.
"Our research found that the proportion of people who progressed was 10% per year in high risk groups and in fact only 5% per year in low risk groups. Moreover only a minority (20-40%) of people developed dementia even after extended follow-up and the risk appeared to reduce slightly with time.
"These results should be seen as positive for those with memory problems even for those that struggle with the kind of memory tests given by the GP or in a memory clinic. There is a large effort to find out who is most at risk of further decline as well to find strategies that might slow down such progress."
GPs have often been reluctant to give a diagnosis of MCI because of its consequences but this current finding should encourage clinicians to identify people with memory problems. Many such individuals stay stable for a long period and a substantial number also improve.
There are at least 1 million people in the UK with MCI without dementia. In February the government announced funding for a specialised memory clinic in every town giving important focus on this often overlooked condition.
Dr. Alex Mitchell | EurekAlert!
Investigators may unlock mystery of how staph cells dodge the body's immune system
22.09.2017 | Cedars-Sinai Medical Center
Monitoring the heart's mitochondria to predict cardiac arrest?
21.09.2017 | Boston Children's Hospital
Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.
A warming planet
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.
The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
19.09.2017 | Event News
12.09.2017 | Event News
06.09.2017 | Event News
22.09.2017 | Life Sciences
22.09.2017 | Medical Engineering
22.09.2017 | Physics and Astronomy