A team of researchers from the Universitat Autònoma de Barcelona (UAB) has cured mice with diabetes type 1 for the first time. In the experiment, the diabetic mice completely recovered from the disease after having suffered excesses of glucose in their blood. Although the mice used were transgenic, the researchers are sure that there will soon be a genic therapy based on this discovery that will cure non-transgenic mice with diabetes type 1, and which, within a few years, will also be able to cure people. The study was published in last edition of Journal of Clinical Investigation.
A research team led by Fatima Bosch, professor in the Department of Biochemistry and Molecular Biology at the UAB, has studied the effects of protein IGF-I on mice with diabetes type 1, i.e. the type of diabetes produced by a decrease in the number of beta cells in the pancreas, the ones which produce insulin. In order to study this effect, the researchers used mice that were genetically modified so that the beta cells in their pancreases would produce protein IGF-I, and have compared the development of diabetes type 1 in this type of mice to the evolution of the disease in control mice (without genetic modifications).
The results of the experiments clearly show that in the transgenic mice with the gene that codifies for protein IGF-I activated in beta cells, the induction of experimental diabetes leads to the replication of these cells, their programmed cellular death is counteracted (apoptosis) and the resident mother cells in the conducts of the pancreas are induced to develop insulin-producing beta cells. All these effects lead to the mice completely recovering from the disease, re-establishing absolutely normal levels of glucose in their blood.
Octavi López Coronado | alphagalileo
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The Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP has been developing various applications for OLED microdisplays based on organic semiconductors. By integrating the capabilities of an image sensor directly into the microdisplay, eye movements can be recorded by the smart glasses and utilized for guidance and control functions, as one example. The new design will be debuted at Augmented World Expo Europe (AWE) in Berlin at Booth B25, October 18th – 19th.
“Augmented-reality” and “wearables” have become terms we encounter almost daily. Both can make daily life a little simpler and provide valuable assistance for...
With the help of artificial intelligence, chemists from the University of Basel in Switzerland have computed the characteristics of about two million crystals made up of four chemical elements. The researchers were able to identify 90 previously unknown thermodynamically stable crystals that can be regarded as new materials. They report on their findings in the scientific journal Physical Review Letters.
Elpasolite is a glassy, transparent, shiny and soft mineral with a cubic crystal structure. First discovered in El Paso County (Colorado, USA), it can also be...
For the first time, Fraunhofer IKTS shows additively manufactured hardmetal tools at WorldPM 2016 in Hamburg. Mechanical, chemical as well as a high heat resistance and extreme hardness are required from tools that are used in mechanical and automotive engineering or in plastics and building materials industry. Researchers at the Fraunhofer Institute for Ceramic Technologies and Systems IKTS in Dresden managed the production of complex hardmetal tools via 3D printing in a quality that are in no way inferior to conventionally produced high-performance tools.
Fraunhofer IKTS counts decades of proven expertise in the development of hardmetals. To date, reliable cutting, drilling, pressing and stamping tools made of...
At AKL’16, the International Laser Technology Congress held in May this year, interest in the topic of process control was greater than expected. Appropriately, the event was also used to launch the Industry Working Group for Process Control in Laser Material Processing. The group provides a forum for representatives from industry and research to initiate pre-competitive projects and discuss issues such as standards, potential cost savings and feasibility.
In the age of industry 4.0, laser technology is firmly established within manufacturing. A wide variety of laser techniques – from USP ablation and additive...
Every three years, the plastics industry gathers at K, the international trade fair for plastics and rubber in Düsseldorf. The Fraunhofer Institute for Laser Technology ILT will also be attending again and presenting many innovative technologies, such as for joining plastics and metals using ultrashort pulse lasers. From October 19 to 26, you can find the Fraunhofer ILT at the joint Fraunhofer booth SC01 in Hall 7.
K is the world’s largest trade fair for the plastics and rubber industry. As in previous years, the organizers are expecting 3,000 exhibitors and more than...
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23.09.2016 | Life Sciences
23.09.2016 | Health and Medicine
23.09.2016 | Life Sciences