Granisetrón is a pharmaceutical drug the efficacy of which against vomiting (antiemetic), when administered orally or intravenously, has already been shown, but never studied when given subcutaneously. The research shows that the antiemetic granisetron, administered subcutaneously, behaves in a similar manner as when injected intravenously. The advantage of the subcutaneous method is the ease of treatment for non-hospitalised patients. For these patients using the intravenous method it is problematic, requiring, as it does, specialised care; while administering orally may involve the patient vomiting.
Home use and emergencies
This is why subcutaneous administration opens new perspectives, providing a comfortable and easy way of home-based treatment, either with self-medication by the patients themselves or administered by their carers, in either case reducing the dependence on trained medical personnel.
The fundamental objective of the work undertaken was, thereby, to demonstrate if it were feasible for the patients themselves to manage to self-medicate the antiemetic in their own homes in case of vomiting as a consequence of chemotherapy treatment. In this way, the patient does not have to go to a hospital in order to control nauseas and vomiting. Nevertheless, this form of medication is also useful for healthcare personnel such as the emergency services.
A total of 30 patients participated in the trial. All were medicated with granisetron, using one of the two forms of administration, intravenous or subcutaneous, during the first cycle of chemotherapy and, in the following cycle, the other alternative was employed. Then a number of blood samples of all the patients were obtained in order to determine the concentration of the pharmaceutical drug in each sample.
The conclusions of the study confirm that the concentrations of granisetron obtained were equivalent in both methods of medication. This is why the research supports the administration of granisetron subcutaneously as a new alternative for the treatment of cancer patients.
Egoitz Etxebeste | alfa
Penn study identifies new malaria parasites in wild bonobos
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17.11.2017 | National Institute of Standards and Technology (NIST)
The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.
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The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
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The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.
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