The study, which started in 2005, comprised 145 pregnant mothers with families at heightened risk of developing allergy and asthma. From the 25th week of pregnancy through the third month of nursing, they were asked to take nine capsules of oil every day. Half of them were given fish oil with high levels of omega-3 fatty acids, and the other half were given a placebo in the form of soybean oil.
The study was doubly blind, that is, neither the participants nor the researchers knew who had received what.
It turned out that the "fish-oil children" had fewer than half as many reactions to eggs at the age of one year as the placebo group did. This is an important discovery, since allergic reactions to eggs early in life are strongly correlated with the later development of allergic disorders like eczema and asthma.
All of the children are now two years old and have undergone a clinical examination regarding eczema, been scratch-tested for eggs, milk, and cats, and left a blood sample.
The idea that the difference is truly an effect of the omega-3 fats is supported by an immunological study of the mothers' blood. The women who were given fish oil had less prostaglandin E2 in their blood than the others. This is a substance that triggers allergic immune responses, and it is known that it is depressed when the concentration of omega-3 increases.
"We have been able to show that omerga-3 influences the mother's immunological profile in a less inflammatory direction. Theoretically this can also affect the child's immune system, which is supported by the results of the scratch-tests," says the immune biologist Malin Fagerås Böttcher, who led the study together in collaboration with the child allergist Karel Duchen.
The study will be complemented during the autumn by an immunological examination of the children's blood and an eczema check-up. The researchers hope also to be able to monitor these children as they grow older to see if they develop air-way allergies.
Contact: Malin Fagerås Böttcher, associate professor, Section for Pediatrics, cell phone: +46 (0)709-549759; phone: +46 (0)13-229538; e-mail: email@example.com
Gustav Löfgren | idw
Laser activated gold pyramids could deliver drugs, DNA into cells without harm
24.03.2017 | Harvard John A. Paulson School of Engineering and Applied Sciences
What does congenital Zika syndrome look like?
24.03.2017 | University of California - San Diego
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
24.03.2017 | Materials Sciences
24.03.2017 | Physics and Astronomy
24.03.2017 | Physics and Astronomy