The authors surveyed 8,755 employees of international companies collecting data on their travel and whether or not they developed thromboses (deep vein thromboses and pulmonary emboli) afterwards. The employees were followed up for a total of 38,910 person-years, during 6,872 of which they were exposed to a long-haul flight. In the follow-up period, 53 thromboses occurred, 22 within 8 wk of a long-haul flight.
The researchers then calculated that there was an incidence rate of 3.2/1,000 thromboses per year exposed to long haul travel compared with 1.0/1,000 per year in individuals not exposed to air travel; this rate is equivalent to a risk of one event per 4,656 long-haul flights.
Venous thrombosis has been linked to air travel since 1951 but despite a number of previous studies the absolute risk of symptomatic venous thrombosis after long-haul travel has not previously been calculated. Knowledge of the absolute risk of symptomatic thrombosis after air travel is important so that travellers can accurately assess their risk of developing thromboses and decide whether prophylactic measures against thromboses are worthwhile.
The authors found that the risk of thromboses increased with exposure to more flights within a short time frame and with increasing duration of flights. The risk was particularly high in employees under age 30 y, women who used oral contraceptives, and individuals who were particularly short, tall, or overweight. The incidence of thromboses was highest in the first 2 weeks after travel and gradually decreased to baseline after 8 weeks.
Although the authors note that this study was performed in a working population with a mean age of 40 y and go on to say that the absolute risk of venous thrombosis in the general population is likely to be higher than the risk found here, they conclude however that “The results of our study do not justify the use of potentially dangerous prophylaxis such as anticoagulant therapy for all long-haul air travellers, since this may do more harm than good. However, for some subgroups of people with a highly increased risk, the risk–benefit ratio may favour the use of prophylactic measures.”
The study was conducted as part of the WRIGHT project (World Health Organization Research In to Global Hazards of Travel), an international research project under the auspices of the World Health Organization.
Andrew Hyde | alfa
How cancer metastasis happens: Researchers reveal a key mechanism
19.01.2018 | Weill Cornell Medicine
Researchers identify new way to unmask melanoma cells to the immune system
17.01.2018 | Duke University Medical Center
On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.
We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...
08.01.2018 | Event News
11.12.2017 | Event News
08.12.2017 | Event News
19.01.2018 | Materials Sciences
19.01.2018 | Health and Medicine
19.01.2018 | Physics and Astronomy