The symptoms from this bug, which is called Clostridium Difficile, range from mild illness to life-threatening colitis. In severely affected patients the inner lining of the colon becomes severely inflamed and sometimes the walls of the colon wear away, causing perforation, which can lead to a life-threatening infection of the abdomen.
“The bug is not as well known as MRSA but in recent years it has been linked to twice as many deaths as the more famous deadly superbug. It is vital that we find out as much about this bug as possible to improve our methods of prevention and treatment of this infection” said Dr Loscher.
Dr Christine Loscher, School of Biotechnology, DCU said “The recent appointments of a number of Immunologists at DCU in both the Schools of Biotechnology and Nursing have added to the existing Immunology research and have allowed the development of this research area over the last few years. This conference is a great opportunity to highlight this research.”
This work is part of a collaborative study with Professor Dermot Kelleher, Consultant Gastroenterologist at St James Hospital and Head of School of Medicine, TCD.
Recent work carried out at DCU has focused on proteins isolated from the coat of the bacteria and identified how they mediate the interaction of this bacteria with the immune system. This research significantly increases our knowledge about how this bacteria initiates infection and subsequent inflammation in the colon. Furthermore, it may provide vital information regarding the susceptibility of certain patients to this infection. Ultimately these recent findings could lead to huge advancements in the prevention and treatment of this infection.
Research will be presented by invited speakers from the US, Europe, UK and Ireland. The research being presented has implications for a wide range of diseases including asthma, cystic fibrosis, tuberculosis, multiple sclerosis and autoimmunity.
Shane Kenny | alfa
Routing gene therapy directly into the brain
07.12.2017 | Boston Children's Hospital
New Hope for Cancer Therapies: Targeted Monitoring may help Improve Tumor Treatment
01.12.2017 | Berliner Institut für Gesundheitsforschung / Berlin Institute of Health (BIH)
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The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
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With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
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Scientists at the Institute of Science and Technology Austria (IST Austria) have managed to control the behavior of individual bacteria by connecting them to a...
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