Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Heeding the WARNing from malaria’s past

06.09.2007
A global network to monitor drug resistance and guide malaria treatment and prevention policies is being launched.

As outlined in a series of articles in the online open access publication, Malaria Journal, the World Antimalarial Resistance Network (WARN) aims to provide a globally co-ordinated effort to tackle the disease, which is estimated to kill between 1 and 2.7 million people every year.

One of the major aims of WARN is to facilitate worldwide monitoring and characterisation of drug resistance, particularly that to the latest generation of antimalarial drugs, artemisinin-based combination therapies (ACTs).

WARN will consist of four linked, global, open-access, web-based databases containing four kinds of data:

·Clinical drug efficacy
·In vitro response of malaria parasites to drugs
·Prevalence of molecular markers of drug resistance
·Pharmacological properties of drugs in different groups of patients.
The databases will include freely available tools to make adding information straightforward, and to give researchers the opportunity to analyse and use information from the databases in a variety of ways. Information on individual patients will be collated in a standardised way, which should make it easier for researchers to compare directly or pool data from different sites across the world.

WARN’s founders hope that the databases will help speed up the publication process for scientists. This, in turn, means that policymakers and malaria control managers will have access to timely information on the temporal and geographic trends of drug resistance, allowing them to take action as soon as resistant malaria parasites are detected.

Drug resistance is a major threat to the control and eradication of malaria and can lead to treatment failure, increased spread of the disease, and higher morbidity and mortality. Many ‘old’ antimalarials, including chloroquine and mefloquine, are now of limited use because of drug resistance.

Today, over 50 countries recommend ACTs as first-line therapy for falciparum malaria, the most severe form of the disease. While these newer treatments are currently effective, researchers know that resistance to ACTs will emerge in the future.

The network is being launched after a meeting of leading malaria researchers and policymakers sponsored by the Bill and Melinda Gates Foundation held at the Wellcome Trust/Sanger Centre, Cambridge, UK in late 2006.

Charlotte Webber | alfa
Further information:
http://www.malariajournal.com/
http://www.biomedcentral.com

More articles from Health and Medicine:

nachricht New malaria analysis method reveals disease severity in minutes
14.08.2017 | University of British Columbia

nachricht New type of blood cells work as indicators of autoimmunity
14.08.2017 | Instituto de Medicina Molecular

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

A Map of the Cell’s Power Station

18.08.2017 | Life Sciences

Engineering team images tiny quasicrystals as they form

18.08.2017 | Physics and Astronomy

Researchers printed graphene-like materials with inkjet

18.08.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>