Differently from myocardial infarction that has comparable incidence and short term mortality, risk stratification models for patient with acutely decompensated heart failure are not available for current clinical practice. The identification of clinical variables able to predict short-term prognosis may be very helpful in guiding medical decision making including the need of a more intensive management in an intensive or a coronary care unit.
The EuroHeart Survey on Heart Failure collected data on 3,579 patients admitted acutely for heart failure by 133 centres in 30 countries. We excluded from this analysis the patients with cardiogenic shock, whose short-term mortality is so high that specific models for risk stratification are less useful since an intensive management is needed in all patients.
The database of the remaining 3,441 patients included in the EuroHeart Survey on Heart Failure showed that in-hospital all-cause mortality of patients with acute decompensation of an already known heart failure condition was 5.3% (116/2202 patients), while total in-hospital mortality of patients with de novo acute heart failure was 5.4% (67/1239 patients).
Even if overall mortality was 5.3%, the mortality risk greatly varied from less than 1% to more than 50% according to the presence or absence of clinical variables that significantly influence in-hospital death. In both situations (worsening or de novo heart failure), the strongest independent predictors of short-term all-cause mortality were the following ones: advanced age, low systolic blood pressure, renal dysfunction, signs of peripheral hypo-perfusion and an acute coronary syndrome as precipitating factor for heart failure. With the exception of age, all these clinical conditions can be appropriately and timely managed to reduce in-hospital mortality.
These simple clinical variables, easy to detect in any clinical setting, can be very helpful in the identification of patients at high risk of early death after hospital admission for acute heart failure, allowing a tailored use of intensive therapeutic strategies including the setting (intensive vs usual) in which the patients may be more appropriately managed.
ESC Press Office | alfa
Hot cars can hit deadly temperatures in as little as one hour
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3D images of cancer cells in the body: Medical physicists from Halle present new method
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The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.
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A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.
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There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?
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So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
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