Dr Lynn Bedford, of the School of Biomedical Sciences, will lead a five-year study after receiving an award from the PDS under its Career Development Awards Scheme, which aims to support the careers of the UK’s most promising individuals working in Parkinson’s research.
Dr Bedford will be using a new genetic model of Parkinson’s to further understanding of how and why nerve cells die. Her research will also take a closer look at the reasons for the formation of Lewy bodies — a build-up of proteins within nerve cells — in the brains of people with Parkinson’s.
This study is aimed at providing a platform for the development of drugs to stop nerve cell death.
Dr Kieran Breen, Director of Research and Development for the Parkinson’s Disease Society, said: “Researchers are the people who make the discoveries and forge the links between different research areas so clearly investing in people is key to furthering our understanding of Parkinson’s.
“The Career Development Awards Scheme is aimed at increasing the number of people involved in Parkinson’s research and encouraging the UK’s top researchers of the future to specialise in Parkinson’s.”
Parkinson’s is a progressive neurological condition caused by the death of nerve cells in the brain that produce the chemical dopamine, which is responsible for movement. The condition affects movements such as walking, talking, and writing. Its three main symptoms are tremor, muscular rigidity, and slowness of movement. Parkinson’s is a very individual condition and the rate and nature of progression varies from person to person.
Dr Bedford said: “I have been involved in Parkinson’s disease research for the last five years so I am delighted to get this Career Development Award. This novel model of Parkinson’s will be crucial in helping to uncover and study why nerve cells die in the region of the brain affected in Parkinson’s disease.
“At Nottingham we have an excellent team who are committed to understanding this model. I look forward to driving this interesting new avenue of research and interacting with individuals, both researchers and clinicians, in the field of Parkinson’s.”
Approximately 120,000 people in the UK have Parkinson’s, and 10,000 are diagnosed with the condition every year. Although more common in people aged over 60, about one in 20 of those diagnosed each year are under 40.
Dr Breen added: “The Parkinson’s Disease Society is very pleased to be funding Dr Bedford’s study. Furthering our understanding of the causes of Parkinson’s will hopefully lead to the development of new treatments for the condition, making a difference to the lives of the 120,000 people in the UK with Parkinson’s.”
The PDS has spent more than £30m on research since 1969, including almost £4m in 2006. Studies funded use basic and applied science as well as health and social care projects to investigate the causes, treatment, prevention and cure for Parkinson’s.
The Parkinson’s Disease Society (PDS) is the UK’s leading authority on all aspects of the condition. The charity campaigns for a better quality of life for people with Parkinson’s. The PDS provides field staff and local information and maintains 300 branches.
Research offers clues for improved influenza vaccine design
09.04.2018 | NIH/National Institute of Allergy and Infectious Diseases
Injecting gene cocktail into mouse pancreas leads to humanlike tumors
06.04.2018 | University of Texas Health Science Center at San Antonio
Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...
Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.
The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...
Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...
In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...
In an article that appears in the journal “Review of Modern Physics”, researchers at the Laboratory for Attosecond Physics (LAP) assess the current state of the field of ultrafast physics and consider its implications for future technologies.
Physicists can now control light in both time and space with hitherto unimagined precision. This is particularly true for the ability to generate ultrashort...
13.04.2018 | Event News
12.04.2018 | Event News
09.04.2018 | Event News
19.04.2018 | Materials Sciences
19.04.2018 | Physics and Astronomy
19.04.2018 | Physics and Astronomy