A University of Calgary, Canada team led by Dr. Robert Myers used administrative data to review over 1500 patients hospitalised for acetaminophen overdose between 1995 and 2004. Since 1995, the hospitalisation rate has dropped 41% from 19.6 per 100 000 population to 12.1 per 100 000 in 2004. Myers’ team found that although for under 50s the rate fell 46%, there was a 50% jump in hospitalisations for the over 50s. Female overdosing fell to a greater extent than it did for males (46% vs. 29%).
The majority of overdoses were intentional (85%), with the remainder made up of 13% accidental cases and 2% homicides or of unclear intent. Accidental overdoses fell between 1995 and 2002, but then began to rise again. Over 100 products are available over the counter, sometimes containing relatively large amounts of acetaminophen. The authors suggest that lack of patient and physician awareness may account for at least part of the increase in accidental overdoses.
In 1998 UK legislation limited packets of acetaminophen to 16 x 500mg tablets. The authors note the overdose rate in Calgary is about one fifth that reported in the UK, despite similar suicide rates. UK acetaminophen overdose cuts have largely been attributed to the package size restrictions, however no such restrictions have been imposed in Canada. Acetaminophen (paracetamol) overdose is the most common cause of acute liver failure, accounting for as many as 50% of acute liver failure cases.
Charlotte Webber | alfa
Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign
Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
20.01.2017 | Awards Funding
20.01.2017 | Materials Sciences
20.01.2017 | Life Sciences