Mikael Hartman from the Karolinska Institute in Stockholm, Sweden led an international team, identifying 2,787 mother-daughter pairs and 831 sister pairs among women with breast cancer diagnosed between 1961 and 2001 from Sweden’s national Multi-Generation Register.
They found that a woman’s breast cancer prognosis predicts the survival of her first-degree relatives with breast cancer. Mothers surviving breast cancer after five years, had daughters with a 91 percent chance of surviving the disease. But only 87 percent of daughters whose mothers had died within five years survived. Being sister to a woman who had died of breast cancer within five years gave a 70 percent chance of survival from breast cancer, whereas chances improved to 88 percent if she had survived. Overall, a poor prognosis for a woman gave first-degree relatives a 60-80 percent higher chance of breast cancer mortality within the five-year timeframe.
Access to health care in Sweden is good irrespective of socio-economic status, so these factors are unlikely to have biased the findings. Women with a mother or sister who has had breast cancer are also likely to be more aware of the disease, making delays in seeking treatment unlikely. As well as genetics, other risk factors such as obesity and hormone replacement therapy probably play a role in the incidence and outcome of breast cancer. Dr Hartman says the findings are “relevant to women with newly diagnosed breast cancer,” and to those treating them. The next step will be to understand what is inherited; tumor biology, response to therapy or vigilance of the immune system.
Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin
Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
24.05.2017 | Event News
23.05.2017 | Event News
22.05.2017 | Event News
26.05.2017 | Life Sciences
26.05.2017 | Life Sciences
26.05.2017 | Physics and Astronomy