Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Impact of very low carbohydrate diets on long-term gut health

18.06.2007
Scientists at Aberdeen’s Rowett Research Institute have shown that a very low carbohydrate weight-loss diet results in a four-fold reduction in the numbers of certain types of bacteria in the gut of obese men. This is a significant finding because these gut bacteria produce a substance called butyrate, which has been shown to be important for keeping the gut healthy including helping to prevent colorectal cancer. The study raises questions about the impact of the prolonged use of very low-carbohydrate weight-loss diets on gut health.

Very low-carbohydrate weight-loss diets (such as the so-called ‘Atkins-type diets) are popular with people struggling to lose weight and are used in some weight-loss clinics. Nutritionists have raised concerns about the low fruit and vegetable content of such diets as these contain nutrients that help protect against a number of diseases and cancers within the body. Less attention has been paid to the consequences of the low carbohydrate intake on the bacteria within the gut and how this might alter the release of either beneficial or harmful compounds from the food.

In this study, 19 healthy, obese men were given three diets containing different levels of carbohydrate (high, medium and low). Two of the diets also contained a high proportion of protein, as this is known to help reduce appetite and is used in a number of diets that help produce weight loss. Indeed, the volunteers lost similar amounts of weight and body fat on these two diets. Stool samples were analysed for the amount and type of bacteria, and for butyrate.

“The changes in butyrate production that we observed in this study are the largest ever reported in a human dietary trial. The results provide strong evidence that butyrate production is largely determined by the content of a particular type of carbohydrate in the diet that the bacteria in our guts can utilise,” said Professor Harry Flint who led the research at the Rowett Institute.

“We can’t be sure from this study about the impact of butyrate production on gut health, but there has been quite a lot of work done which shows that butyrate stops cancer cells from growing, and so helps prevent colorectal cancer.

“If low carbohydrate diets are to be consumed for long periods of time, it may be important to ensure that there is enough of the right sort of carbohydrate in the diet which can be used by the bacteria to produce compounds such as butyrate, which are beneficial for human health. This means making sure you continue to eat plenty of sources of fibre – such as fruit and vegetables,” said Professor Harry Flint.

The work is published in Applied and Environmental Microbiology, 73:1073-8.

Sue Bird | alfa
Further information:
http://www.rowett.ac.uk

More articles from Health and Medicine:

nachricht Organ-on-a-chip mimics heart's biomechanical properties
23.02.2017 | Vanderbilt University

nachricht Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

From rocks in Colorado, evidence of a 'chaotic solar system'

23.02.2017 | Physics and Astronomy

'Quartz' crystals at the Earth's core power its magnetic field

23.02.2017 | Earth Sciences

Antimicrobial substances identified in Komodo dragon blood

23.02.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>