Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

A new zest for life

30.05.2007
How the treatment of common thyroid disease reduces tiredness and the risk factors for heart disease.

Putting on weight and feeling lethargic?

Then new research from Newcastle University and funded by Gateshead NHS Foundation Trust shows it is worth having your thyroid levels checked – as these can be symptoms of thyroid disease which is easily identified and treated.

Known medically as sub clinical hypothyroidism, it is characterised by a shortage of the hormone thyroxine and often precedes an underactive thyroid.

It affects up to 16% of women and 6% of men, becoming more prevalent with age.

The research has shown that treatment of subclinical hypothyroidism with thyroid hormone reduces tiredness, cholesterol and reduces the risk factors for heart disease by improving the markers of atherosclerosis or hardening of the arteries.

In the study, patients undergoing 12 weeks of thyroxine treatment saw a reduction in their amount of LDL cholesterol, reversed weight gain - losing on average half a kilo, felt less tired and had reduced their risk factors for heart disease.

Until recently many doctors considered this condition not worthy of treatment. Now a new study led by Dr Jolanta Weaver of Newcastle University and Gateshead NHS Foundation Trust published in this month’s issue of The Journal of Clinical Endocrinology and Metabolism shows that treatment leads to significant improvements for patients.

In the largest trial to date, 100 participants with persistent subclinical hypothyroidism were given thyroxine and compared with those taking a placebo or dummy medication.

Dr Salman Razvi and Dr Jolanta Weaver of Newcastle University’s School of Clinical Medical Sciences carried out a pivotal crossover study. They assessed common heart disease risk factors such as the level of LDL, or “bad”, cholesterol, body weight and endothelial function, which is a very early marker of hardening of the arteries. They also asked participants to rate their quality of life.

This treatment did not cause any side-effects.

Dr Weaver says, “The results of our study show that treatment of people with this mild form of underactive thyroid condition leads to significant improvements in risk factors for ischemic heart disease and symptoms of tiredness.”

Patients with subclinical hypothyroidism are being encouraged to discuss their treatment with their doctors.

CASE STUDY
Mrs Frances King, 56, from Dunston, Gateshead, UK.
“I took part in the study because I was first diagnosed with a borderline underactive thyroid 27 years ago but never had any treatment.

I‘d never been ill but always had a lack of energy and generally felt tired and lethargic. As soon as I was put on the medication I noticed a difference. Since the trial I’ve been back to my GP and have been prescribed thyroxine. I now have more energy and feel brighter.

I’ve battled with my weight for years but since getting the medication I’ve lost a couple of stones because I’m more motivated to do things. I’ve got a real zest for life - I run up the stairs, I’ve got the energy to walk the dogs and I’m out gardening which I hadn’t been doing.”

Michael Warwicker | alfa
Further information:
http://www.ncl.ac.uk/press.office/press.release/content.phtml?ref=1180452564

More articles from Health and Medicine:

nachricht 3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg

nachricht Better equipped in the fight against lung cancer
16.05.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

Im Focus: Computer-Designed Customized Regenerative Heart Valves

Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers from the University of Zurich, the Technical University Eindhoven and the Charité Berlin have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time.

Producing living tissue or organs based on human cells is one of the main research fields in regenerative medicine. Tissue engineering, which involves growing...

Im Focus: Light-induced superconductivity under high pressure

A team of scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg investigated optically-induced superconductivity in the alkali-doped fulleride K3C60under high external pressures. This study allowed, on one hand, to uniquely assess the nature of the transient state as a superconducting phase. In addition, it unveiled the possibility to induce superconductivity in K3C60 at temperatures far above the -170 degrees Celsius hypothesized previously, and rather all the way to room temperature. The paper by Cantaluppi et al has been published in Nature Physics.

Unlike ordinary metals, superconductors have the unique capability of transporting electrical currents without any loss. Nowadays, their technological...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Supersonic waves may help electronics beat the heat

18.05.2018 | Power and Electrical Engineering

Keeping a Close Eye on Ice Loss

18.05.2018 | Information Technology

CrowdWater: An App for Flood Research

18.05.2018 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>