The scientific approach to allergies has evolved explains Pierre-Henri Benhamou of France’s DBV technologies. Aside from the well-known ‘immediate’ forms of allergy, which involve rapid acute symptoms upon allergen ingestion, ‘delayed’ types have also been described since the 1990s. Here, clinical symptoms, usually digestive or cutaneous reactions, occur several hours, days or even weeks after. “These allergies are caused by foods that form the base of the day-to-day diet,” says Benhamou, “and to which the patient becomes only gradually sensitised. Unlike the more traditional forms of allergy, the delayed forms pose important problems in terms of diagnosis.”
“What’s different about the ‘DIALLERTEST’ system is that it uses DBV’s new E-patch technology,” explains Benhamou. “This allows us to set dry powdered milk onto the patch by means of electrostatic forces. Thus, no additive or wet substance is needed to hold the suspected allergen in place. This represents an important simplification of the patch test.” It means that a much tighter control over the quantity of allergen is delivered, a more measurable and reproducible reaction, and, ultimately, more reliable and standardised screening for cow’s milk protein allergy. It will also allow doctors to keep allergens in their best reactive state, the powdered form. The materials used in ‘DIALLERTEST’ patch tests are all bio-compatible, specially conceived for the pharmaceutical industry.
At the beginning of 2006, new investors SOFINOVA and APAX contributed 12 million euro to DBV Technologies, providing further impetus to their work on child allergy detection and treatment systems. The company is now working in several related directions, collaborating with laboratories and universities both in Europe and the United States. Benhamou says the Nutricia laboratory, a world leader in infant nutrition, has agreed to undertake the commercial marketing of ‘DIALLERTEST’, confirming one of the most outstanding success stories in recent years the field of child allergies.
“With support from EUREKA and thanks to a particularly dynamic research team, DBV has developed a range of completely original tests,” he says, “creating strong commercial alliances on the basis of an extremely original and innovative concept. In cooperation with our Polish partner P.P.F. Hasco-Lek. Today, our products are being distributed in Mexico, Australia and the countries of the ex-USSR, and the necessary paperwork is also being completed for distribution in the US and with the European drug agency (EMEA).”
Sally Horspool | alfa
Laser activated gold pyramids could deliver drugs, DNA into cells without harm
24.03.2017 | Harvard John A. Paulson School of Engineering and Applied Sciences
What does congenital Zika syndrome look like?
24.03.2017 | University of California - San Diego
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
24.03.2017 | Materials Sciences
24.03.2017 | Physics and Astronomy
24.03.2017 | Physics and Astronomy