Necrotising enterocolitis is an infection which attacks and kills the lining of the bowel and affects mainly premature infants.
Dr Sanjay Patole, King Edward Memorial Hospital for Women, Perth, Western Australia, Australia, and colleagues studied the results of seven trials involving babies born at 33 weeks or earlier and less than 1.5kg in body weight.
In a meta-analysis (a study which combines the results of previous trials) the researchers found the risk of contacting necrotising enterocolitis was reduced by 64% and the risk of death reduced by 53% in groups of premature babies given probiotics compared to the control groups. The risk of sepsis occurring in babies was not significantly different between the groups given probiotics and the control groups.
And the time taken for the premature babies to achieve full feeds was less when they were given probiotic supplements, by an average of nearly three days.
The authors say: “The remarkably consistent results, despite the distinct differences in dose, timing, and types of organism used, suggest that substantial latitude might be available in the choice of an effective probiotic regimen in the design of further trials.”
They conclude: “If a large, well designed-trial confirms our results, it could make a very strong case for the routine use of probiotics in preterm neonates.”
In an accompanying comment, Dr Carlo Caffarelli, Paediatric Clinic, University of Parma, Italy, said: “The usual measures for the prevention of necrotising enterocolitis are feeding with human milk and delaying preterm delivery. The overview by Patole and colleagues is an important step towards an evidence-based use of probiotics.
“However, further large trials are needed before recommending these promising agents.”
Tony Kirby | alfa
Resolving the mystery of preeclampsia
21.10.2016 | Universitätsklinikum Magdeburg
New potential cancer treatment using microwaves to target deep tumors
12.10.2016 | University of Texas at Arlington
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
21.10.2016 | Health and Medicine
21.10.2016 | Information Technology
21.10.2016 | Materials Sciences