Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Heart Problems Caused By Continued Cocaine Abuse Highlighted

04.05.2007
The heart problems caused by sustained cocaine abuse are highlighted in a Case Report published in this week’s edition of The Lancet.

The report focuses on a 31-year-old Italian man who turned up at the Emergency Department of the Siena General Hospital during 2005 suffering chest pain, dyspnoea and fatigue. He had no previous medical history but admitted longstanding cocaine misuse. Dr Valerio Zacà and colleagues at the hospital treated the man and authored this Case Report.

Tests revealed the left ventricle in the patient’s heart had dilated to 80mm. The heart was also moving weakly and was not contracting properly. He was subsequently diagnosed with dilated cardiomyopathy (swollen heart with damaged muscle) caused by cocaine misuse.

He was discharged on a regimen of drugs including warfarin, and in the months following received drug counselling and tested negative for cocaine at a series of unscheduled urine tests. He reported back for further tests in September 2006 and his left ventricular diameter had reduced to 57mm, and the contractile function of the heart was also much improved.

In recent years, cocaine use has risen to epidemic proportions in the USA and Europe. The observation of cardiovascular complications associated with cocaine use has become progressively more frequent.

The authors say: “A history of cocaine use should be considered when assessing previously healthy young patients with heart disease.”

They add that cocaine is well known to cause myocardial ischaemia (shortage of blood to the heart) and infarction (death of heart muscle). There is also evidence of an increase prevalence of left ventricular systolic dysfunction in long term cocaine abusers.

The drug also causes microscopic changes similar to those observed in patients with phaeochromocytoma (a tumour of the adrenal gland which causes excess adrenaline production, leading to heart palpitations and other symptoms).

The authors conclude: “Debate continues over whether, and how, cardiomyopathy caused by cocaine use can resolve on abstinence. We hypothesise that abstinence allows recovery from sympathetic overstimulation, rather like surgical removal of a phaeochromocytoma.”

Tony Kirby | alfa
Further information:
http://www.thelancet.com/webfiles/images/clusters/thelancet/press_office/Cardiomyopathy.pdf

More articles from Health and Medicine:

nachricht PET imaging tracks Zika virus infection, disease progression in mouse model
20.09.2017 | US Army Medical Research Institute of Infectious Diseases

nachricht 'Exciting' discovery on path to develop new type of vaccine to treat global viruses
18.09.2017 | University of Southampton

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Tiny lasers from a gallery of whispers

New technique promises tunable laser devices

Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

Im Focus: Quantum Sensors Decipher Magnetic Ordering in a New Semiconducting Material

For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.

Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...

Im Focus: Fast, convenient & standardized: New lab innovation for automated tissue engineering & drug

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...

Im Focus: Silencing bacteria

HZI researchers pave the way for new agents that render hospital pathogens mute

Pathogenic bacteria are becoming resistant to common antibiotics to an ever increasing degree. One of the most difficult germs is Pseudomonas aeruginosa, a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

Molecular Force Sensors

20.09.2017 | Life Sciences

Producing electricity during flight

20.09.2017 | Power and Electrical Engineering

Tiny lasers from a gallery of whispers

20.09.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>