Professor Chris Griffiths, Centre for Health Sciences, Queen Mary’s School of Medicine and Dentistry, London, UK and colleagues did their outreach study on 50 general practices in Hackney, East London, UK, to promote screening for tuberculosis in primary care. The practices were divided into two groups of 25: intervention and control.
The research team found that detection rates for active tuberculosis in intervention practices were 13% higher than those in the control group, while detection rates for the latent form of the disease were also 10% higher in the practices with the screening programme. And the rates of BCG vaccination against Tuberculosis were seven times higher for the practices implementing screening against the control group.
The authors say: “A seven fold increase in BCG overage in people aged five and over represents a striking improvement, since most interventions boost immunisation in primary care by five to 20 per cent.”
Hackney was selected as it is one of just 19 local authorities across England, Wales and Northern Ireland which has yearly tuberculosis rates of more than 40 per 100,000 – this is the threshold rate above which tuberculosis is defined as common in that area. Of these 19 authorities, 16 are in London. Migrants from Africa and Eastern Europe (which has hot spots of multi-drug resistant tuberculosis) are resident in high numbers in these areas (poor, inner city), and tend not to disperse for economic and social reasons.
The authors conclude: “Our study suggests screening could have a clinically important effect, should have useful generalisability, and could be recommended as part of tuberculosis control initiatives in industrialised countries.”
In an accompanying comment, Dr David Mant of the Department of Primary Health Care, University of Oxford, UK and Dr Richard Manyon-White, of the Directorate of Public Health, Oxford, UK, say: “An educational research programme and additional local services will be useful in regions in developed countries where migrants cluster and tuberculosis rates are high.
“In the UK, the next step should be applications of the lessons learnt in East London to other areas where tuberculosis is common. In the long term, however, developed countries will gain most by supporting the tuberculosis control strategies in the rest of the world.”
Tony Kirby | alfa
Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University
The first analysis of Ewing's sarcoma methyloma opens doors to new treatments
01.12.2016 | IDIBELL-Bellvitge Biomedical Research Institute
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water
In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
05.12.2016 | Power and Electrical Engineering
05.12.2016 | Materials Sciences
05.12.2016 | Power and Electrical Engineering