Professor Chris Griffiths, Centre for Health Sciences, Queen Mary’s School of Medicine and Dentistry, London, UK and colleagues did their outreach study on 50 general practices in Hackney, East London, UK, to promote screening for tuberculosis in primary care. The practices were divided into two groups of 25: intervention and control.
The research team found that detection rates for active tuberculosis in intervention practices were 13% higher than those in the control group, while detection rates for the latent form of the disease were also 10% higher in the practices with the screening programme. And the rates of BCG vaccination against Tuberculosis were seven times higher for the practices implementing screening against the control group.
The authors say: “A seven fold increase in BCG overage in people aged five and over represents a striking improvement, since most interventions boost immunisation in primary care by five to 20 per cent.”
Hackney was selected as it is one of just 19 local authorities across England, Wales and Northern Ireland which has yearly tuberculosis rates of more than 40 per 100,000 – this is the threshold rate above which tuberculosis is defined as common in that area. Of these 19 authorities, 16 are in London. Migrants from Africa and Eastern Europe (which has hot spots of multi-drug resistant tuberculosis) are resident in high numbers in these areas (poor, inner city), and tend not to disperse for economic and social reasons.
The authors conclude: “Our study suggests screening could have a clinically important effect, should have useful generalisability, and could be recommended as part of tuberculosis control initiatives in industrialised countries.”
In an accompanying comment, Dr David Mant of the Department of Primary Health Care, University of Oxford, UK and Dr Richard Manyon-White, of the Directorate of Public Health, Oxford, UK, say: “An educational research programme and additional local services will be useful in regions in developed countries where migrants cluster and tuberculosis rates are high.
“In the UK, the next step should be applications of the lessons learnt in East London to other areas where tuberculosis is common. In the long term, however, developed countries will gain most by supporting the tuberculosis control strategies in the rest of the world.”
Tony Kirby | alfa
Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign
Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
20.01.2017 | Awards Funding
20.01.2017 | Materials Sciences
20.01.2017 | Life Sciences