Services that help women understand the way that their inherited genetic make-up influences their risk of getting breast cancer ease distress and decrease their levels of cancer worry. There is, however, insufficient evidence to make recommendations about the best way of delivering these services.
These findings came from a Cochrane Systematic Review of data contained in five papers that reported trials in which a total of 1251 women were given a risk assessment that helped them understand their individual risk of getting cancer.
Current research is revealing much about the way that a person’s genes influence their risk of breast cancer. Consequently, this is increasing the demand for information, reassurance, screening and genetic testing. The challenge is to ensure that this information is handled in ways that patients can understand, and that enables them to make informed choices.
“As the demand for cancer genetics services is likely to increase, there will be a pressing need for finding the best ways of delivering these services,” says Dr Rachel Iredale, one of the researchers on the project, who works at the Institute of Medical Genetics in Cardiff.
“The challenge is to develop cancer genetic services that adequately reassure inappropriately worried individuals while at the same time identifying those at moderate or high risk who require further information, management and support,” says co-researcher Stephanie Sivell.
A risk assessment takes time. Typically, the first step is to draw up a family tree marking on any relatives who had, or still have, breast cancer and the ages at which they were diagnosed. Women may then be placed in a low, medium or high risk group. From here, cancer genetic services can move on to provide information and support to patients and their families, offer genetic counselling and may undertake genetic testing for women who are at increased risk of familial breast cancer.
“All of these services need to be carried out with care as genetic information touches on sensitive issues, such as reproductive decision-making, employment and insurance,” says Iredale.
Jennifer Beal | alfa
Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan
Prospect for more effective treatment of nerve pain
20.02.2017 | Universität Zürich
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
21.02.2017 | Earth Sciences
21.02.2017 | Medical Engineering
21.02.2017 | Trade Fair News