Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

The CIMA from the University of Navarra and a Dutch scientific center have found a treatment for porphyria

30.03.2007
The Center for Applied Medical Research (CIMA) from the University of Navarra and the Amsterdam Molecular Therapeutics BV (AMT) have demonstrated the pre-clinical effectiveness of a treatment against acute intermittent porphyria. Once the pre-clinical, toxicological and clinical phases are completed, it may be possible to eliminate this disease permanently.

The research on this hereditary disease has been developed in the Area of Genetic Therapy and Hepatology of the CIMA. Dr. Jesús Prieto coordinated the research, which was carried out by scientists Gloria González Aseguinolaza, Astrid Pañeda, Rubén Hernández Alcoceba and Antonio Fontanellas. The symptoms of this disease appear when there are anomalies in the production of heme, a basic substance for the synthesis of vital proteins such as hemoglobin, myoglobin and cytochrome.

Among the problems that this disease causes, which until now have been incurable, are included internal neuropsychological disturbances and severe stomach pains. As well, acute attacks of porphyria can be fatal if they cause grave neurological complications.

Persons affected will intermittently suffer from the symptoms of porphyria throughout their entire life. Upon occasion, they appear in adolescence and more frequently in adulthood, with greater occurrence in women. Some medicines, such as barbiturates, tranquilizers and sedatives, can trigger the disease; as well as diets, hormonal irregularities, tobacco, alcohol, infections or emotional and physical stress.

After testing the effectiveness of the treatment, the CIMA and the AMT have obtained exclusive rights to synthesize and develop the medications. Currently, the clinical phase is scheduled to begin in 2008 and the treatments should be available to the public in 2010.

Egoitz Etxebeste | basqueresearch
Further information:
http://www.elhuyar.com
http://www.basqueresearch.com/berria_irakurri.asp?Gelaxka=1_1&hizk=I&Berri_Kod=1255

More articles from Health and Medicine:

nachricht Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan

nachricht Prospect for more effective treatment of nerve pain
20.02.2017 | Universität Zürich

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Switched-on DNA

20.02.2017 | Materials Sciences

Second cause of hidden hearing loss identified

20.02.2017 | Health and Medicine

Prospect for more effective treatment of nerve pain

20.02.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>