Authors of a French study in this week’s issue of THE LANCET highlight the link between a specific strain of the bacterium Staphylococcus aureus and a severe form of pneumonia in children.
Between 1986 and 1998, eight cases of community-acquired pneumonia due to S aureus strains carrying the gene for the Panton-Valentine leukocidin (PVL) were recorded in France, six of which were fatal. Jerome Etienne from the Centre Hospitalo-Universitaire of Lyon, France, aimed to assess the clinical features of these eight cases, and those of other cases identified prospectively, and to compare them with the characteristics of patients with pneumonia caused by PVL-negative strains.
Eight retrospective and eight prospective cases of PVL-positive S aureus pneumonia were compared with 36 cases of PVL-negative S aureus pneumonia. The investigators recorded age, length of hospital stay, risk factors for infection, signs and symptoms, laboratory findings, antibiotic treatment, and serial radiological findings for all patients.
Richard Lane | alphagalileo
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