The two-year study involved 242 elderly men with Parkinson disease in Tokyo, Japan. Half of the group received the drug risedronate and vitamin D2. The remaining men received placebo and vitamin D2.
The study found the men taking risedronate were three times less likely to sustain a hip fracture compared to the placebo group.
Researchers also found bone mineral density (BMD) among men taking risedronate increased by 2.2 percent and decreased by nearly three percent in the placebo group. In addition, researchers found a biomarker for bone loss decreased by nearly 47 percent in the risedronate group and 33 percent in the placebo group.
"Prior to the study, these men had been experiencing a rapid rate of bone loss due to inactivity. Our findings show risedronate, along with vitamin D2, effectively controls the progression of osteoporosis, and reduces the risk of hip fractures," said study author Yoshihiro Sato, MD, with Mitate Hospital in Tokyo.
Sato says the findings also show risedronate is stronger than the drug alendronate, which has been found in previous studies to reduce bone loss and prevent hip fractures in elderly women with Parkinson disease.
Side effects of risedronate included inflammation of the esophagus and abdominal pain, which eventually healed with appropriate therapy, according to the study.
Angela Babb | EurekAlert!
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In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
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A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
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The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
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