The centre is a result of a partnership between a group of academic and medical institutions committed to translating research into patient care. These are UCL's Institute of Neurology and Institute of Child Health, the University of Newcastle, University College London Hospitals NHS Foundation Trust (UCLH), Newcastle Hospitals NHS Trust, and Great Ormond St Hospital for Children (GOSH). It can draw on significant populations of affected patients at the partner hospitals and a wealth of basic science and translational expertise, which will ensure major benefits to the treatment of patients with neuromuscular disease throughout the UK.
The external international peer review undertaken by the MRC stated that this centre had the potential to lead the world in this area.
"Although there have been impressive advances in understanding the molecular basis of many neuromuscular diseases, this has not yet been translated into clear patient benefit or new treatments. We have identified a number of key obstacles to delivering this translational benefit and the centre aims to specifically address each of them. By uniting an impressive team of experts in London and Newcastle, we are hoping to make progress in tackling these diseases," say Professors Mike Hanna, Director, and Martin Koltzenburg, Deputy Director of the new centre.
UCL Institute of Neurology (IoN)
Roger Lemon, Director of the Institute of Neurology, said: "The mission of the IoN is to carry out high quality research in the basic, clinical and translational neurosciences. Together with our associated specialist hospital, The National Hospital for Neurology and Neurosurgery, (UCLH), the Institute promotes translation of research that is of direct clinical relevance to improved patient care and treatment. As a Postgraduate Research Institute of UCL we also carry out an important role in teaching and training researchers for careers in clinical neuroscience. There are major groups undertaking basic and clinical research in neuromuscular disease that will play a major role in the new centre."
UCL Institute of Child Health (ICH)/ Great Ormond Street Hospital for Children (GOSH)
ICH and GOSH are the country’s only Biomedical Academic Centre specialising in paediatrics, and the largest centre for paediatric research and training outside the US. They form the leading centre for paediatric neurosciences in the UK. Both are consistently rated excellent in their research and the joint centre is of world class significance. Both have long established links with the National Hospital for Neurology (and UCLH more broadly) and the Institute of Neurology. Professor Martin Koltzenburg, Neurosciences Theme leader at ICH, will be a Deputy Director of the Centre.
“The impact of breakthroughs in basic medical science on understanding the cause of many neuromuscular diseases has been enormous and this will lead to major improvements in diagnosis and treatment in the years ahead. The development of the new MRC translational research centre brings together many of the best scientists in the UK in this field and puts us in a strong position to lead the world in translational neuromuscular research.” said Professor Edward Byrne, incoming Dean of the UCL Faculty of Biomedicine.
UCL Provost, Professor Malcolm Grant, added: "We welcome the establishment of this centre at the UCL Institute of Neurology and thank the MRC for their generous contribution and ongoing support. The centre will play a major role in the advancement of scientific knowledge in this field and, most vitally, in the development of treatments to improve the lives of those who suffer from these debilitating neuromuscular conditions."University College London Hospitals NHS Foundation Trust (UCLH)
University of Newcastle
The University of Newcastle has a long history of research excellence in neuromuscular diseases, and the four PIs (Professors Bushby, Struab, Turnbull and Chinnery) together with the incoming Professor of Experimental Myology, Professor Hanns Lochmeuller, represent a very strong grouping with expertise in a range of different neuromuscular diseases in children and adults. The translational strength of the centre is reflected in the recent award of an EU centre of excellence co-ordinated from Newcastle in this field of research, TREAT-NMD. Professor Bushby will be a Deputy Director of the Centre.
Dominique Fourniol | alfa
Nanoparticles as a Solution against Antibiotic Resistance?
15.12.2017 | Friedrich-Schiller-Universität Jena
Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University
DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
11.12.2017 | Event News
08.12.2017 | Event News
07.12.2017 | Event News
15.12.2017 | Power and Electrical Engineering
15.12.2017 | Materials Sciences
15.12.2017 | Life Sciences