Dr Douglas Tincello, Senior Lecturer at the University’s Department of Cancer Studies and Molecular Medicine and Consultant Gynaecologist at the Leicester General Hospital, is carrying out a randomised trial involving injecting botulinum toxin into the bladders of women who have overactive bladder disease.
The trial, which has received a grant of £158,000 from the Moulton Charitable Trust, involves women whose conditions have not improved after tablet treatment.
Overactive bladder is a condition in which the bladder tries to empty itself, rather than the patient retaining control. Symptoms include having to pass water very often day and night, not being able to put off the need to do so, sudden urgency to pass water and sometimes incontinence.
The botulinum toxin relaxes the bladder muscle so it cannot squeeze so hard, and so reduces the need to pass water frequently or suddenly. It may also reduce the sensation of having a full bladder.
Dr Douglas Tincello commented: “Overactive bladder is very difficult to treat well. Lots of our patients try different tablets and pelvic floor exercises but at least a third of them will not be better. At the moment the only alternatives are to put up with it, or consider a very big operation which often means the patient ends up with a stoma bag.
“Many patients just suffer in silence, but the quality of life when you live with overactive bladder is similar to that of a patient on kidney dialysis.
“Botulinum toxin has been tested already in spinal cord injury patients.This study is important to ascertain if it is safe and effective in patients with overactive bladder. Botulinum toxin is a very exciting development and in the future may provide a simple and effective way to improve the quality of life in our patients."
Alex Jelley | alfa
Penn studies find promise for innovations in liquid biopsies
30.03.2017 | University of Pennsylvania School of Medicine
'On-off switch' brings researchers a step closer to potential HIV vaccine
30.03.2017 | University of Nebraska-Lincoln
The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
30.03.2017 | Health and Medicine
30.03.2017 | Health and Medicine
30.03.2017 | Medical Engineering