Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Smoking increases risk of TB infection

28.02.2007
People who smoke have a greater risk of becoming infected with tuberculosis (TB) and of having that infection turn into active TB disease, according to an analysis by researchers at the University of California, Berkeley.

The authors of the study, published in the Feb. 26 issue of the journal Archives of Internal Medicine, analyzed 24 studies that included details about smoking and TB outcomes. They found that smokers have a 73 percent greater chance of becoming infected than do non-smokers. For those who are infected, the chances of developing active TB disease are about 50 percent greater in smokers, compared with non-smokers. Overall, a smoker has about a 2.5 times greater risk of contracting active TB than does a non-smoker in the same population.

"Our study is the first systematic, quantitative assessment of TB risks from smoking," said lead author Michael Bates, adjunct professor of epidemiology at UC Berkeley's School of Public Health. "There have been mixed opinions on whether smoking has any relevance to TB. Our review and analysis of the research in this area indicates that there is a connection, and that smoking is a major risk factor for TB."

The results indicate that TB control policies should incorporate tobacco control as one of the preventive interventions, the researchers said.

According to the World Health Organization (WHO), nearly 2 billion people, or one-third of the world's population, are infected with Mycobacterium tuberculosis, the bacteria responsible for TB. The bacteria can remain latent in the body for decades, kept in check by a normal immune system. However, if the immune system becomes compromised, the bacteria can multiply and cause active TB disease.

"Active TB is often fatal, particularly if left untreated," said Kirk Smith, UC Berkeley professor of environmental health sciences and senior author of the paper. "The risk factors that lead to latent TB infection becoming active are still not well understood, but this study shows that smoking is probably one of the most important. It could be that smoking suppresses the respiratory immune system, allowing latent infections to blossom. Smoking also seems to make people more susceptible to becoming infected in the first place."

In 2003, 8.8 million people worldwide developed active tuberculosis, and each year, an estimated 1.7 million people die from TB.

"Because it increases the number of active TB cases, we estimate that smoking is related to half a million of the 1.7 million TB deaths each year," said Smith.

The researchers noted that concern about TB is growing as the number of HIV infections, which often lead to TB, increases. The increase in multi-drug resistant TB strains is making it more difficult to treat active infections, the researchers added.

"TB is very difficult to deal with," said Smith. "There is a lot of worry about TB in the world. The standard methods of dealing with it - such as finding people who are infected and then treating them - are barely holding ground. Effective prevention measures are needed to help in the battle."

The researchers said that reducing smoking could be an important element in efforts to control TB. "Currently, smoking cessation is not a part of TB control programs," said Bates. "The evidence from this study suggests that it should be."

Sarah Yang | EurekAlert!
Further information:
http://www.berkeley.edu

More articles from Health and Medicine:

nachricht Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan

nachricht Prospect for more effective treatment of nerve pain
20.02.2017 | Universität Zürich

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Switched-on DNA

20.02.2017 | Materials Sciences

Second cause of hidden hearing loss identified

20.02.2017 | Health and Medicine

Prospect for more effective treatment of nerve pain

20.02.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>