New evidence supports the link between a cause of the common cold and more severe respiratory infections such as pneumonia and acute bronchitis. The study is published in the March 15 issue of The Journal of Infectious Diseases, now available online.
Rhinoviruses are among the most common viral infections, and are responsible for at least 50 percent of all common colds. Although the association between rhinoviruses and other acute respiratory illnesses in children is increasingly accepted and has been shown in previous reports, the new study is the first to determine age-specific rates of hospitalization across the entire population of two counties. This study shows that the link between rhinoviruses and hospitalizations is especially strong when children have a history of wheezing or asthma.
The study, conducted by E. Kathryn Miller, MD, MPH, and colleagues at Vanderbilt University, the Centers for Disease Control and Prevention, and the University of Rochester, surveyed children under the age of 5 years admitted with fever and respiratory symptoms in Davidson County, Tenn. (which includes Nashville) and Monroe County, N.Y. (which includes Rochester) over a one-year period.
Their results showed that of the 592 children involved in the study, 26 percent tested positive for rhinovirus, representing almost 5 rhinovirus-associated hospitalizations per 1000 children. The study detected more rhinoviruses (26 percent) than respiratory syncytial viruses (20 percent), which have been considered the major cause of respiratory infections in infants and children.
These findings are particularly important given the age-specific rates of hospitalization observed. Among children 0-5 months, there were 17.6 hospitalizations per thousand; among those age 6-23 months, 6.0 per thousand; and among those 24-59 months, 2.0 hospitalizations per thousand. Miller remarked, "This study shows that rhinoviruses are associated with hospitalizations for fever and respiratory illnesses, even in young infants."
Children with a history of wheezing or asthma had more than eight times as many rhinovirus-associated hospitalizations than those without such a history. Asthma was the only significant factor that distinguished children hospitalized with rhinoviruses from those with other viruses or no viruses. Of those hospitalized with a history of asthma or wheezing, rhinoviruses were found in 36 percent of children aged 0-2 years and in 48 percent of children aged 2-5 years. According to Miller, the finding that asthma was the only risk factor significantly associated with rhinovirus hospitalizations should indicate that "patients with asthma might be particularly good candidates for prevention and treatment strategies for rhinovirus infection."
As a next step to their study, Miller suggested, "additional studies over multiple years in multiple geographic regions are needed to more completely understand the role of rhinoviruses in hospitalizations in children. As discussed in our study, rhinoviruses are sometimes found in healthy children; thus, further studies are required to determine the actual rate of ‘carriage’ in healthy children as opposed to those who are sick or have had recent symptoms of illness. There should also be further investigation into the question, ‘Why are children with asthma disproportionately burdened by the "common cold" virus?’"
In an accompanying editorial, Ronald B. Turner, MD of the University of Virginia School of Medicine, noted the value of studies on rhinoviruses because of their frequency and huge cost to society. Turner echoed Miller’s sentiment, remarking that the study should stimulate future research into the medical implications of rhinoviruses.
- Rhinoviruses cause at least half of all common colds.
- The study found 26 percent of the hospitalized children had rhinovirus infections—more than were infected with a virus previously thought to be the main cause of serious respiratory illness.
- Children with a history of wheezing or asthma had more than eight times as many rhinovirus-associated hospitalizations than those without.
Steve Baragona | EurekAlert!
Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin
Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
In the race to produce a quantum computer, a number of projects are seeking a way to create quantum bits -- or qubits -- that are stable, meaning they are not much affected by changes in their environment. This normally needs highly nonlinear non-dissipative elements capable of functioning at very low temperatures.
In pursuit of this goal, researchers at EPFL's Laboratory of Photonics and Quantum Measurements LPQM (STI/SB), have investigated a nonlinear graphene-based...
24.05.2017 | Event News
23.05.2017 | Event News
22.05.2017 | Event News
24.05.2017 | Physics and Astronomy
24.05.2017 | Physics and Astronomy
24.05.2017 | Event News