Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Diuretic pills not recommended for preventing pre-eclampsia

24.01.2007
Although they were prescribed widely in the 1960s to women looking to avoid dangerously high blood pressure during pregnancy, diuretic drugs should not be recommended as a way to prevent this serious condition, called preeclampsia, according to a recent review of studies.

Women who took diuretics -- commonly known as "water pills" -- during pregnancy were not any less likely to develop preeclampsia, to deliver prematurely or to lose their babies than those who did not take the pills, said obstetrician David Churchill of New Cross Hospital in West Midlands, England, and colleagues.

However, women who took diuretics were significantly more likely to have nausea and vomiting.

"From this review, no clear benefits have been found from the use of diuretics to prevent preeclampsia," Churchill said.

The review included five studies and 1,836 women.

The review appears in the latest issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.

Women with preeclampsia, usually diagnosed after 20 weeks of pregnancy, have high blood pressure and protein in their urine. The condition can be dangerous for both mother and fetus, causing pregnancy complications, early delivery and even death.

"Currently, the only cure for the disease is delivery of the baby and the placenta, but this leads to many babies being born prematurely and vulnerable," Churchill said.

For this reason, doctors have focused on diet changes, such as prescribing more calcium-rich foods and other treatments that may prevent the condition before it appears, rather than searching for ways to lessen its effects, said Lisa Bodnar, Ph.D., a maternal nutrition specialist at the University of Pittsburgh.

"There are no changes that a woman can make that will lessen symptoms or 'cure' her disease once she has overt preeclampsia. The dietary modifications that women should make are in early pregnancy, or even before a woman gets pregnant," Bodnar said.

Researchers and doctors originally prescribed diuretics to prevent preeclampsia because they thought the condition was caused by excess salt and water retained by pregnant women. Diuretics increase urination and remove water and salt from the body that can cause serious symptoms in liver, kidney and heart disease, including high blood pressure.

However, doctors stopped recommending diuretics as a regular preventive measure in the 1980s when studies began to link the pills with a decrease in pregnant women's plasma levels, the liquid part of blood that carries blood cells. Plasma levels normally increase as part of a healthy pregnancy.

Diuretics are still prescribed to pregnant women, although less than they used to be.

Lisa Esposito | EurekAlert!
Further information:
http://www.cfah.org

More articles from Health and Medicine:

nachricht Laser activated gold pyramids could deliver drugs, DNA into cells without harm
24.03.2017 | Harvard John A. Paulson School of Engineering and Applied Sciences

nachricht What does congenital Zika syndrome look like?
24.03.2017 | University of California - San Diego

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>