Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Hypertension, prehypertension in young linked with heart enlargement

10.01.2007
American Heart Association rapid access journal report

Hypertension and prehypertension in adolescents and young adults was associated with a higher risk of having an abnormally enlarged heart, researchers report in Circulation: Journal of the American Heart Association.

In a study of American Indians, average age 26.5, those with hypertension or prehypertension were more likely to have changes in the heart structure associated with increased cardiovascular risk: higher left ventricular wall thickness, higher left ventricular mass and higher prevalence of left ventricular hypertrophy. The prevalence of left ventricular hypertrophy was three times higher among those with hypertension and two times higher among those with prehypertension, compared to those with normal blood pressure.

Left ventricular hypertrophy is an abnormal thickening of the muscles of the heart's left ventricle (main pumping chamber). It is associated with heart and blood vessel complications, such as heart failure.

"The findings are a wake-up call for increased preventive measures to head off heart disease with lifestyle modifications, such as reducing caloric intake and increasing physical activity in this population," said Richard B. Devereux, M.D., senior study author and professor of medicine at Weill Medical College of Cornell University in New York City.

"At these younger ages, the increasing prevalence of early-onset hypertension and prehypertension is associated with changes in the heart that are related to worsened prognosis for heart disease, disability and death," he said.

Prehypertension is defined as systolic blood pressure higher than 120 mmHg but lower than 140 mmHg, or a diastolic pressure greater than 80 mmHg but lower than 90 mmHg, or both. Hypertension is defined as a systolic blood pressure greater than 140 mmHg or a diastolic blood pressure greater than 90 mmHg. Prehypertension is a relatively new category of blood pressure established by the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC-7). Devereux said this is the first large population-based study to examine the heart changes associated with the new JNC-7 category of hypertension.

"Previous research has found little difference comparing middle-aged to elderly overweight hypertensive white, black and American-Indian adults, suggesting that Indian populations are not unique, and may provide a preview of what other populations may experience as overweight and obesity rates increase," he said.

Researchers analyzed the association of prehypertension and early-onset hypertension with clinical characteristics and changes in heart structure and function in 1,944 participants (57.5 percent women) of the Strong Heart Study, an ongoing study of cardiovascular risk factors and disease in 13 American-Indian communities.

In data collected from health examinations conducted between July 2001 and September 2003, researchers found early-onset hypertension in 294 participants (15 percent) and prehypertension in 675 participants (35 percent).

Both hypertensive and prehypertensive participants were more likely to be men, obese, have diabetes, and have impaired fasting glucose. Hypertensive and prehypertensive participants had higher average pulse pressure (the difference between systolic and diastolic blood pressure values), stroke volume index (related to the volume of blood the heart pumps out at each beat), and total peripheral resistance index (a reflection of how constricted peripheral blood vessels are – peripheral constriction causes blood pressure to rise). There was an early prevalence of increased arterial stiffness with multiple features related to insulin resistance.

"The frequency of heart abnormalities in these younger participants is similar to that found in the middle-age or adult population of hypertensives who are at risk for adverse events," Devereux said.

Jennifer S. Drukteinis, M.D., lead author of the study and an internal medicine resident at Weill Medical College of Cornell University, said the implications are clear: "There needs to be vigilant monitoring of blood pressure at younger and younger ages. Obesity and high blood pressure go hand-in-hand, and lifestyle modification is the key."

Karen Astle | EurekAlert!
Further information:
http://www.heart.org

More articles from Health and Medicine:

nachricht NTU scientists build new ultrasound device using 3-D printing technology
07.12.2016 | Nanyang Technological University

nachricht How to turn white fat brown
07.12.2016 | University of Pennsylvania School of Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

NTU scientists build new ultrasound device using 3-D printing technology

07.12.2016 | Health and Medicine

The balancing act: An enzyme that links endocytosis to membrane recycling

07.12.2016 | Life Sciences

How to turn white fat brown

07.12.2016 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>