Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Bronchiolitis – best practice summed up

19.12.2006
An “umbrella review” published in the latest edition of Evidence-Based Child Health: A Cochrane Review Journal neatly summaries the evidence base for the various treatment options for bronchiolitis. The review highlights the lack of treatment for a frequently experienced illness, and points to the urgent need for research.

What is bronchiolitis?

Bronchiolitis is the most common severe lower respiratory infection in infants. It occurs when a viral infection causes infants’ lower airways to become inflamed. They have difficulty breathing, sleeping and feeding.

What is its incidence?

Bronchiolitis affects 10-20% of infants under the age of two. Three percent of these are admitted to hospital, meaning that around 1.8 million infants are taken to US hospitals each year. Of these, 2.7% need intensive care, 1.5% need ventilation and 0.2% die.

Clinical comment

If there is no respiratory distress, feeding difficulties or specific risk factors, the infant can be treated at home with advice on when to return for re-assessment. If there are respiratory problems infants should be hospitalized and clinical treatment is normally limited to ensuring the infant is given adequate fluids, and oxygen. This can allow time for the infant to recover. Nebulised epinephrine may produce marginal relief, and could help some infants go home. The effect, however, is mild.

Various treatments have been tried in patients who are more severely affected, but none produce any marked effects. Bronchodilators and epinephrine produce no benefits, though some people suggest they may reduce restlessness and sleeplessness. Similarly, neither injecting steroids or immunoglobulins, nor giving vibration or percussive physiotherapy reduces symptoms.

A clear need for research

“What we need is a large randomised trial that carefully studies all of the currently available therapies and sees whether adjusting dose, type or frequency of treatment can produce greater benefit – then we need to examine new-comers,” says Dr. Michael Smith, author of the review, who works in the Department of Paediatrics, Craigavon Area Group Hospital Trust, Craigavon, Northern Ireland.

Evidence-Based Child Health: A Cochrane Review Journal is available online via Wiley InterScience, the online content service at: www.evidence-basedchildhealth.com

Polly Young | alfa
Further information:
http://www.evidence-basedchildhealth.com

More articles from Health and Medicine:

nachricht Usher syndrome: Gene therapy restores hearing and balance
25.09.2017 | Institut Pasteur

nachricht MRI contrast agent locates and distinguishes aggressive from slow-growing breast cancer
25.09.2017 | Case Western Reserve University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: LaserTAB: More efficient and precise contacts thanks to human-robot collaboration

At the productronica trade fair in Munich this November, the Fraunhofer Institute for Laser Technology ILT will be presenting Laser-Based Tape-Automated Bonding, LaserTAB for short. The experts from Aachen will be demonstrating how new battery cells and power electronics can be micro-welded more efficiently and precisely than ever before thanks to new optics and robot support.

Fraunhofer ILT from Aachen relies on a clever combination of robotics and a laser scanner with new optics as well as process monitoring, which it has developed...

Im Focus: The pyrenoid is a carbon-fixing liquid droplet

Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.

A warming planet

Im Focus: Highly precise wiring in the Cerebral Cortex

Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.

The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...

Im Focus: Tiny lasers from a gallery of whispers

New technique promises tunable laser devices

Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

Fraunhofer ISE Pushes World Record for Multicrystalline Silicon Solar Cells to 22.3 Percent

25.09.2017 | Power and Electrical Engineering

Usher syndrome: Gene therapy restores hearing and balance

25.09.2017 | Health and Medicine

An international team of physicists a coherent amplification effect in laser excited dielectrics

25.09.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>