Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Regular and moderate physical activity is beneficial for patients with heart failure

EVGN research proves that aerobic training attracts endothelial progenitor cells able to heal damaged tissues

People with heart failure tend to think that they should avoid physical efforts, in order to prevent the worsening of the already compromised cardiac functions. But a joint research carried out by EVGN scientists and other Italian partners proved that the opposite is true.

The investigation was performed by Patrizio Sarto from the Department of Cardiology and Sport Medicine of the General Hospital Noale-Mirano (Venice) – together with researchers from the Department of Laboratory Medicine and the Laboratory of Molecular and Cell Biology (Oncology Department of the Azienda Ospedaliera ASL 13) – in collaboration with a European Vascular Genomics Network (EVGN, group led by Roberto Latini from the Istituto di Ricerche Farmacologiche Mario Negri (Milano). Regular physical activity performed at least three times a week by people who suffer from heart failure, of course under the supervision of an expert personal trainer, has the power to attract the endothelial progenitor cells (EPC) towards those areas where they perceive tissue damages, and where they are ready to heal the wound.

The investigation lasted eight weeks, during which the scientists examined 23 patients with heart failure, aged between 57 and 69. The volunteers underwent regular exercise (three times a week) under the control of a trained personal trainer, in charge of verifying a number of cardiac and body parameter to avoid the excessive fatigue to the participants. “Each session was one hour long” explains Patrizio Sarto. “But we did not monitor just the physical conditions of these subjects: we also took blood samples at four different time points during the two months of training. The analysis of their blood cells gave us critical information on the effects of the gymnastic on these people”.

After the first physical sessions, in fact, the blood of these patients showed an increased number of endothelial progenitor cells. What is the meaning of this observation? “These data – comments Latini – suggests that physical activity can mobilize and gather EPCs in specific areas where the cells are able to regenerate damaged tissues such as the cardiac one in people with heart failure. Besides, these cells can also promote the growth of injured blood vessels and increase the angiogenesis rate (that is the number of newborn vessels that sprout in these areas)”. The beneficial effects of exercising were certainly well-known. But the EVGN research presented yesterday in Toulouse sheds light on the biochemical mechanisms that make the regular physical exercise a highly recommended activity.

The European Vascular Genomics Network (EVGN) is the first Network of excellence on cardiovascular disease funded by the European Commission under the 6th Framework Programme "Life sciences, genomics and biotechnology for health" (Contract Number: LSHM-CT-2003-503254).

The Conference is supported by an unrestricted educational grant from Laboratoires SERVIER.

Francesca Noceti | alfa
Further information:

More articles from Health and Medicine:

nachricht Inflammation Triggers Unsustainable Immune Response to Chronic Viral Infection
24.10.2016 | Universität Basel

nachricht Resolving the mystery of preeclampsia
21.10.2016 | Universitätsklinikum Magdeburg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Oasis of life in the ice-covered central Arctic

24.10.2016 | Earth Sciences

‘Farming’ bacteria to boost growth in the oceans

24.10.2016 | Life Sciences

Light-driven atomic rotations excite magnetic waves

24.10.2016 | Physics and Astronomy

More VideoLinks >>>