"Our study demonstrates that exercise when young may reduce the risk of fractures later in life, and the old exercise adage of 'use it or lose it' may not be entirely applicable to the skeleton," said the study's principal investigator, Stuart J. Warden, assistant professor and director of research in physical therapy at the Indiana University School of Health and Rehabilitation Sciences at IUPUI.
Researchers exercised the right forearms of 5-week-old female rats for a few minutes three times a week for seven weeks. The left forearms were not exercised. Bone quantity and structure of the rats' right and left forearms were assessed before and after exercise. Researchers did not exercise the rats for the next 92 weeks -- virtually their entire lifespan. At that point, their forearm bones were assessed again for bone quantity and structure, as well as strength.
All procedures were performed following approval of the Institutional Animal Care and Use Committee of Indiana University.
"We knew that exercise increases bone size and strength, and that the skeleton is most responsive to exercise during the crucial growing years around puberty when you reach adult size and strength," Warden said. "We also knew that bones are not as responsive to exercise when you are older."
What was not known, however, was if the skeletal benefits of exercising while young would last a lifetime, Warden said. In other words, he said, "can you use activity while young to offset the risk of osteoporosis, or the risk of bone fractures, later in life""
The study determined the answer to that question is, "Yes," Warden said.
The researchers found that the rats retained all of the skeletal exercise benefits they obtained while young even though they hadn't exercised for the rest of their lives, Warden said.
"We found the exercise resulted in a lifetime increase in bone size in the right forearms of the rats and the bones of the left forearms never caught up in size," he said.
How big a bone is determines how resistant it is to bending, or how strong it is, he said.
As humans age, bone loss occurs from the inside surface of the bone outward, Warden noted. Exercising while young lays down additional outside layers of bone. This results in a bigger bone than otherwise would be the case.
"With more bone layers on the outside, you have more bone to lose," Warden said.
By making the right forearm bones bigger during growth in their study, the researchers found these bones to be stronger, or more resistant to fracture, than left forearm bones despite exercise being ceased a lifetime ago.
The study demonstrates the importance of childhood exercise that stimulates the skeleton, like basketball or jumping, Warden said. Short periods of exercise several times a week are all that is needed to stimulate bone development in children, he added.
The message to older adults, however, remains the same. Even though the best time to gain lifetime bone health benefits is while people are young, exercising when people are older is essential to maintain bone mass and balance, as well as maintain aerobic fitness, all of which aid in reducing the risk of low-trauma (osteoporotic) fractures associated with aging.
Chances to treat childhood dementia
24.07.2017 | Julius-Maximilians-Universität Würzburg
World first: Massive thrombosis removed during early pregnancy
20.07.2017 | Universitätsspital Bern
3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects
A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...
Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.
For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...
What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.
To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...
The research team of Prof. Dr. Oliver Einsle at the University of Freiburg's Institute of Biochemistry has long been exploring the functioning of nitrogenase....
A one trillion tonne iceberg - one of the biggest ever recorded -- has calved away from the Larsen C Ice Shelf in Antarctica, after a rift in the ice,...
21.07.2017 | Event News
19.07.2017 | Event News
12.07.2017 | Event News
24.07.2017 | Power and Electrical Engineering
24.07.2017 | Materials Sciences
24.07.2017 | Materials Sciences