Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Second opinion yields treatment changes for half of patients

01.12.2006
Consultation with multidisciplinary tumor board leads to different interpretation, new breast cancer treatment recommendations

More than half of breast cancer patients who sought a second opinion from a multidisciplinary tumor board received a change in their recommended treatment plan, according to a new study from the University of Michigan Comprehensive Cancer Center.

A multidisciplinary tumor board includes a network of specialists from different disciplines devoted to treating breast cancer, including surgery, radiation oncology, medical oncology, radiology and pathology.

Researchers looked at the records of 149 consecutive patients referred to the U-M Cancer Center’s multidisciplinary breast tumor board for a second opinion. The patients had already been diagnosed with breast cancer after having undergone initial evaluation, breast imaging and biopsy, and they already had a treatment recommendation from another hospital or care provider.

Overall, 52 percent of the patients evaluated had one or more changes in their recommendations for surgery. The changes were a result of breast imaging specialists reading a mammogram differently or breast pathologists interpreting biopsy results differently. In some cases, the initial recommendation was changed after the case was reviewed by medical oncologists and radiation oncologists prior to surgery.

Results of the study appear in the Nov. 15 issue of the journal Cancer.

“A multidisciplinary tumor board that involves the collaborative effort of multiple medical specialties allows expert opinion and recommendations based on the most recent research findings. Meanwhile, the patients come to only one setting, with no need to visit multiple specialists individually,” says study author Michael Sabel, M.D., assistant professor of surgery at the U-M Medical School and part of the U-M Cancer Centers multidisciplinary breast tumor board.

The study authors found the initial treatment recommendations often did not consider new surgery techniques, such as delivering chemotherapy before surgery to make breast conservation possible or sentinel lymph node biopsy, a new technique to determine whether cancer has spread beyond the breast. Thirty-two percent of patients had their surgery recommendations changed based on a multidisciplinary approach to surgical management

The researchers found radiologists re-interpreted imaging results in 45 percent of patients, in some cases identifying previously undiagnosed second cancers. More than a quarter of patients were recommended to undergo another biopsy. Previous studies have documented variation in how radiologists interpret mammograms. Those who specialize in breast imaging tend to detect more abnormalities.

In addition, a dedicated breast pathologist can make a difference in how the cancer is staged, which in turn can affect treatment recommendations. In this study, the tumor board pathologists interpreted test results differently in 29 percent of patients. For some patients, this meant a change in diagnosis, for other patients it affected the aggressiveness of their tumor.

U-M established one of the first multidisciplinary breast care centers in 1985 to provide comprehensive diagnosis and treatment for women with benign or malignant disease. U-M currently has multidisciplinary clinics in 11 tumor types.

Nicole Fawcett | EurekAlert!
Further information:
http://www.mcancer.org

More articles from Health and Medicine:

nachricht New study points the way to therapy for rare cancer that targets the young
22.11.2017 | Rockefeller University

nachricht Penn study identifies new malaria parasites in wild bonobos
21.11.2017 | University of Pennsylvania School of Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Frictional Heat Powers Hydrothermal Activity on Enceladus

Computer simulation shows how the icy moon heats water in a porous rock core

Heat from the friction of rocks caused by tidal forces could be the “engine” for the hydrothermal activity on Saturn's moon Enceladus. This presupposes that...

Im Focus: Nanoparticles help with malaria diagnosis – new rapid test in development

The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.

Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

Underwater acoustic localization of marine mammals and vehicles

23.11.2017 | Information Technology

Enhancing the quantum sensing capabilities of diamond

23.11.2017 | Physics and Astronomy

Meadows beat out shrubs when it comes to storing carbon

23.11.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>