Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Better protection for the neonatal brain

22.11.2006
Around one in ten children is born preterm. The brain is particularly vulnerable in preterm infants. Insults during this time of brain development can subsequently lead to motor deficits, cognitive limitations, attention deficits, learning difficulties and even severe disabilities.

Within the EU project NEOBRAIN (Neonatal Estimation Of Brain Damage Risk And Identification of Neuroprotectants), scientists will collaborate in order to identify strategies to diagnose and to protect the newborn brain against such insults.

International partners

In NEOBRAIN, small and medium enterprises collaborate with academic research groups. The project links scientists from a total of 13 partner institutions. The involvement of the companies provides a unique opportunity for using the research results in product development without delay. Publication of project findings in high-profile journals will disseminate new research results and resulting applications on an international level. Scientific coordinator for the entire EU project NEOBRAIN is Prof. Dr. Olaf Dammann from Hannover Medical School, Germany. Patent research and press information will be coordinated in Innsbruck.

Name of participating organisation (Short name,City, Country)
Medizinische Hochschule Hannover (MHH, Hannover, Germany)
BIOCRATES life sciences GmbH Innsbruck (BIOCRATES, Innsbruck, Austria)
BrainZ (BrainZ, Auckland, New Zealand)
Bioanalyt GmbH (BIOANALYT, Potsdam, Germany)
THERAPTOSIS S.A. (THERAPTOSIS, Paris, France)
NEUROPHARMA (NEUROPHARMA, Madrid, Spain)
University Medical Center Utrecht (UMCU, Utrecht, Netherlands)
Göteborgs universitet (UGOT, Gothenborg, Sweden)
Institut National de la santé et de la Recherche Médicale (INSERM, Paris, France)
Université de Genève-Hôpitaux Universitaires de Genève (UNIGE, Geneva, Switzerland)
Charité Universitätsmedizin Berlin (CHARITÉ, Berlin, Germany)
Università degli Studi di Siena (UNISI, Siena, Italy)
Lunds Universitet (ULUND, Lund, Sweden)
Economic impact
Medical progress has reduced infant death considerably. This also means that the number of preterm babies that survive is rising steadily. Of the roughly four million live births per year within the EU, 40,000 preterm babies are at highest for brain damage. Almost half the individuals with cerebral palsy (41 percent) are born preterm.

In addition to the worry for parents and relatives of prematurely born children, the increasing number of premature babies also has economic effects: across the EU, between six and seven billion euros per year are spent on treating premature babies. It is not possible to apply the results of medical research obtained in adults reliably to premature babies. Therefore the medical profession faces the problem that not only is there no marker for early diagnosis of brain damage, there is also no prophylaxis or therapy that protects the brain.

New approaches in research

It is precisely at this point that the NEOBRAIN comes in. The EU research project, which runs for three years, aims to:

1. find biomarkers for early brain damage. In various animal tests the mechanisms leading to brain damage will be investigated. Moreover, a clinical study of children born before the 28th week of pregnancy is planned in order to develop marker profiles.

2. develop strategies for protecting the brain. Here too animal tests will be carried out. Only the most promising results will find their way into clinical research.

3. create a clinical platform as research network for future European and international studies.

4. develop medication within the three year project period and beyond.

The results of neonatal basic research will thus feed directly into clinical research. New findings and therapeutic approaches gained in this way will be introduced rapidly into clinical practice in neonatal intensive care.

NEOBRAIN budget
- project volume 4.4 million euros
- grant volume 3.3 million euros

Mag. Uwe Steger | alfa
Further information:
http://www.neobrain.eu

More articles from Health and Medicine:

nachricht Cystic fibrosis alters the structure of mucus in airways
29.06.2017 | University of Iowa Health Care

nachricht Mice provide insight into genetics of autism spectrum disorders
28.06.2017 | University of California - Davis

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making Waves

Computer scientists use wave packet theory to develop realistic, detailed water wave simulations in real time. Their results will be presented at this year’s SIGGRAPH conference.

Think about the last time you were at a lake, river, or the ocean. Remember the ripples of the water, the waves crashing against the rocks, the wake following...

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Nanostructures taste the rainbow

29.06.2017 | Physics and Astronomy

New technique unveils 'matrix' inside tissues and tumors

29.06.2017 | Life Sciences

Cystic fibrosis alters the structure of mucus in airways

29.06.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>