"Although physicians are aware that Hodgkin's lymphoma survivors are at increased risk of heart disease, it hasn't been well-established how to best monitor these patients," said Aileen Chen, M.D., M.P.P, lead author of the study and a radiation oncologist at the Dana-Farber Cancer Center in Boston. "Our study shows that lipid screening in Hodgkin's survivors is cost effective and provides physicians with a guideline on how frequently they should be screening for high cholesterol, an important risk factor for heart disease."
Hodgkin's lymphoma survivors who received radiation therapy to the chest to cure their cancer are at an increased risk of heart disease compared to the general population because the heart (located in the chest cavity) receives a small amount of radiation when the nearby lymph nodes are treated. Hodgkin's survivors who have high cholesterol are more likely to develop heart disease.
Lipid screening tests are simple blood tests that check the level of lipids or cholesterol in the blood. A high level of cholesterol increases the chance of having heart disease which can lead to heart attacks. If caught early, this condition can be treated with cholesterol-lowering medications.
Dr. Chen's study compared lipid screening every five years starting five years after treatment versus no lipid screening in a cohort of 25-year-old Hodgkin's survivors treated with chest radiation. Patients who screened positive for high cholesterol were treated with statins, a type of cholesterol-lowering medication which has been shown to reduce the risk of heart attacks and death from heart disease. The study found that patients who had lipid screening, with statin therapy, if needed, lived six months longer than those who had no screening test.
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Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
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