"Our study demonstrates that it is feasible for patients to receive IMRT in their own communities without sacrificing high-quality care," said Ajay Bhatnagar, M.D., principal investigator of the study and chief resident, department of radiation oncology, University of Pittsburgh School of Medicine. "This is possible through an integrated network in which treatment is standardized across all cancer centers."
According to study results, there were no significant differences in toxicity profiles and recommended radiation dose prescriptions in 758 prostate cancer patients treated with IMRT at 12 separate community cancer centers and one academic flagship facility. All 13 centers, connected through a telemedicine network, followed the same clinical pathway guidelines for the radiotherapy management of prostate cancer, which included specific details on volumes for radiation treatment planning and recommended doses of IMRT.
"By standardizing planning and treatment for IMRT, patients who live in remote locations can benefit from the same quality of care available at a large academic medical center," said Dwight E. Heron, M.D., study co-author and associate professor of radiation oncology, University of Pittsburgh School of Medicine and director of radiation oncology, University of Pittsburgh Medical Center (UPMC). "Bringing advanced radiation therapy to community locations can have a very positive effect on a patient's quality of life by relieving the anxiety and stress of traveling for treatment."
IMRT treatment planning for the centers was performed at one central location, D3 Radiation Planning, located in Pittsburgh, Pa. Through telemedicine capabilities, medical physicists based at D3 collaborated with radiation oncologists at community locations to develop individualized treatment plans for the patients.
"D3 has worked closely with UPMC physicians in developing standardized approaches for IMRT treatment planning for prostate cancer," said Robin Green, CEO of D3. "Centralizing the treatment planning and delivery process can provide an effective and efficient way to consistently provide high-quality treatment."
Clare Collins | EurekAlert!
Penn vet research identifies new target for taming Ebola
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Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
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At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
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Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.
The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...
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