The risk of heart disease is increased in relation to social deprivation and in people from ethnic minorities such as British Asians. This is not accounted for in currently used risk scores which are therefore potentially unfair.
Doctors use a 'risk score' to decide which patients have the greatest chances of developing heart disease and stroke. They then use the score to prioritize them for preventive treatment.
Until now, the risk score has been based on levels of smoking, blood pressure and fats (cholesterol and HDL cholesterol) in the blood, along with the patient's age and sex.
The Dundee researchers, working with the Scottish Intercollegiate Guidelines Network (SIGN), have produced a new risk score, known as ASSIGN, which includes added information on social deprivation and family history to provide a more complete picture of the risk. Their research is published in the journal `Heart'.
The team, from the Cardiovascular Epidemiology Unit of The Institute of Cardiovascular Research at the University of Dundee (TICR), tracked the health of more than 13,000 men and women aged 30 - 74 in Scotland over 10-20 years to the end of 2005. This information was used to develop the ASSIGN score.
The project leader, Professor Hugh Tunstall-Pedoe says, "Existing scores, such as that from Framingham in the USA use levels of smoking, blood pressure and fats in the blood along with patient's age and sex to estimate risk. However, we know that socially deprived people and people from ethnic minorities such as British Asians are at increased risk, not explained by these factors. A year ago we showed that for this reason the Framingham score was unfair to those people in the population at greatest risk of heart disease. Now by adding in social deprivation and family history we have created a new score, ASSIGN, which is fairer."
The new ASSIGN score is being evaluated for potential adoption in Scotland, and possibly elsewhere. The work was carried out in relation to the development of forthcoming revised guidelines on heart disease by SIGN (the Scottish Intercollegiate Guidelines Network). It was funded by the Scottish Executive Health Department and the British Heart Foundation.
Anna Day | alfa
Researchers release the brakes on the immune system
18.10.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
Norovirus evades immune system by hiding out in rare gut cells
12.10.2017 | University of Pennsylvania School of Medicine
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.
It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...
17.10.2017 | Event News
10.10.2017 | Event News
10.10.2017 | Event News
20.10.2017 | Information Technology
20.10.2017 | Materials Sciences
20.10.2017 | Interdisciplinary Research