"Using IMRT, we are able to dramatically reduce the painful side effects of radiation, thereby improving the patient's quality of life," said Jean-Philippe Pignol, M.D., Ph.D., lead author of the study and a radiation oncologist at Sunnybrook Health Sciences Centre in Toronto, Canada. "Patients should be aware that breast IMRT has fewer side effects than standard radiation therapy and is now widely available."
The current standard of care for breast cancer is surgical removal of the cancer, followed by radiation to the breast to kill any remaining cells. The standard radiation technique uses two opposite radiation beams on the whole breast to target the cancer and can cause excess amounts of radiation to certain areas of the breast, increasing the risk of the patient developing sensitive, red, weepy skin that may blister and peel. The majority (80 percent) of severe skin burns occur on the breast crease, located between the bottom of the breast and the chest wall.
Using IMRT, however, radiation oncologists are able to control the intensity of each beam to better spare nearby healthy tissue, thereby minimizing the risk of too much radiation on a part of the breast and severe skin reactions. The treatment was able to significantly reduce this occurrence in women with large breasts, who are more likely to have severe skin reactions.
In this study, 358 patients were randomly assigned to receive either the standard breast radiation treatment or breast IMRT and were observed during and for six weeks after treatment.
Electrical 'switch' in brain's capillary network monitors activity and controls blood flow
27.03.2017 | Larner College of Medicine at the University of Vermont
Laser activated gold pyramids could deliver drugs, DNA into cells without harm
24.03.2017 | Harvard John A. Paulson School of Engineering and Applied Sciences
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
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