Clinical and regulatory changes must be made to asthma management to ensure it reflects current scientific understanding of the disease, and the needs of patients, say asthma experts. These conclusions form part of the ‘Brussels Declaration’, defining changes that need to be made in order to improve outcomes for asthma patients, developed by leading asthma experts, together with EU policymakers, regulators and patient groups attending the ‘Summit for Change in Asthma Management’, which took place at the EU Parliament on 18th and 19th October 2006.
Key areas for action identified during the Summit, hosted by Liberal Democrat MEP, Liz Lynne (UK) and co-chaired by leading asthma expert Professor Stephen Holgate of the University of Southampton (UK) include: a rapid need to update national and international clinical guidelines on the treatment of asthma, including the EMEA Guidance Note on Asthma; ensure all patients and professionals fully understand the current thinking behind asthma management; inclusion of wider measures of asthma control in studies and practice, which take into account patient quality of life. In addition, the EU Parliament was encouraged with making asthma, its research and its management a political priority through mechanisms such as the European Parliament Initiative Report.Professor Holgate defines the Summit and the resulting Declaration as a great step forward for asthma management and patients: “This meeting has been extremely valuable as it has allowed health care professionals, scientists and patient groups to work directly with regulators and policymakers to establish where and how improvements need to be made in order for asthma patients to receive optimum treatment. However, our work does not end here; it is vital that all of the actions agreed upon are also acted upon to ensure asthma patients benefit fully.”
During the Summit various clinicians presented information which showed asthma to be a systemic inflammatory disease which affects more than just the lungs and thus the need to control inflammation is essential. However, current guidelines and practice are based on a historical view of diagnosis and treatment of asthma which only measure airflow in the lungs and so may not truly capture whether the inflammation is under control or whether other parts of the body are affected by the same type of inflammation. Furthermore, data also shows that patients respond differently to treatments and one option may not suit all. Therefore treatment should be individualised to meet the needs of the patient. Unfortunately, current methods of assessing therapies that influence the wider aspects of allergic inflammation are not reflected in guidelines which currently are restrictive in their recommendations and limit the choice of treatments available for clinicians to choose from.
The Cost of Asthma
It is estimated that over 30 million people in Europe have asthma and the number is rising.1 In addition, deaths from asthma have reached 180,000 annually 2 and the economic cost of asthma in Europe is thought to be in the region of €17 billion per year with an annual productivity loss estimated at €9.8bn.3 The economic and social costs of asthma are largely due to uncontrolled disease, and are likely to rise as its prevalence, complexity and severity increases4 and therefore improvement in disease control would substantially reduce costs.
Rosie Allan | alfa
Correct connections are crucial
26.06.2017 | Charité - Universitätsmedizin Berlin
One gene closer to regenerative therapy for muscular disorders
01.06.2017 | Cincinnati Children's Hospital Medical Center
An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.
Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...
Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.
Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...
Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.
As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...
Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.
With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...
Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine
Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...
19.06.2017 | Event News
13.06.2017 | Event News
13.06.2017 | Event News
26.06.2017 | Life Sciences
26.06.2017 | Physics and Astronomy
26.06.2017 | Information Technology