Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Bacteria increase risk of lower stomach cancer, decreases risk of upper

18.10.2006
The bacteria Helicobacter pylori substantially increase the risk of cancer in the lower stomach, but it may decrease the risk of cancer near the junction between the esophagus and the stomach, according to a study in the October 19 Journal of the National Cancer Institute. This finding may help explain the changing rates and distributions of these cancers in Western countries over the past century.

Infection with H. pylori, which is known to cause ulcers, has also been associated with certain types of gastric cancer, but the strength of association varies with where the cancer is located in the stomach. Two types of gastric cancer commonly exist -- cardia, or cancer of the upper stomach joining the esophagus; and noncardia, or cancer of the lower stomach.

A group of researchers led by Farin Kamangar, M.D., Ph.D., of the National Cancer Institute in Bethesda, Md., selected 234 cardia and noncardia gastric cancer patients in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study and matched them to controls. They assessed all of the subjects for H. pylori infection by testing their blood for antibodies that indicate prior infection.

The authors found that the subjects infected with H. pylori had a higher risk of developing noncardia gastric cancer and a lower risk of developing cardia gastric cancer. They suggest that a decrease in H. pylori infections during the past century may be one reason that scientists have observed increasing rates of cardia and decreasing rates of noncardia gastric cancers in Western countries.

"The results of this study suggest that caution may be warranted against mass treatment to eradicate H. pylori ," the authors write.

In an accompanying editorial, Olof Nyren, M.D., Ph.D., of the Karolinska Institute in Sweden, and William J. Blot, Ph.D., of the International Epidemiology Institute in Rockville, Md., write, "It seems prudent to include the putative protective effect of H. pylori against adenocarcinoma of the esophagus or cardia in the equation when drawing up prevention plans for gastric cancer."

Ariel Whitworth | EurekAlert!
Further information:
http://www.oxfordjournals.org

More articles from Health and Medicine:

nachricht Laser activated gold pyramids could deliver drugs, DNA into cells without harm
24.03.2017 | Harvard John A. Paulson School of Engineering and Applied Sciences

nachricht What does congenital Zika syndrome look like?
24.03.2017 | University of California - San Diego

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>