Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Lung cancer: New techniques improve radiation therapy

11.10.2006
Lung cancer is the second most common malignant tumor in men after prostate carcinoma; in Germany alone, about 27,000 men develop the disease every year. But the incidence of lung tumors is increasing in women, too.

However, so far only 10 to 15 percent of lung cancer patients can be cured permanently. More than half of the patients with a small-cell lung carcinoma and about 65 percent of the patients with a non-small-cell lung carcinoma receive radiation treatment in the course of their illness.

The precision of a three-dimensional radiation planning is, however, limited by nature in the case of lung cancer: During breathing, the tumors shift by a few centimeters. As a consequence, the target area "moves" and can be missed if the radiation limits have been chosen too narrowly. Then the tumor cells will keep growing. But if the radiotherapist chooses the limits of the radiation field too generously, more side effects in the healthy lung are to be expected.

Image guided radiotherapy.

The image guided radiotherapy (IGRT) offers a solution to this dilemma, as experts report at the ESTRO congress in Leipzig. Novel linear accelerators that are equipped with a special x-ray device depict the tumor immediately before the radiation treatment. This allows capturing "moving" target areas. The device registers whether the planned situation matches the real situation. If this is not the case, the computer calculates the deviation, and the radiation table is shifted accordingly.

Respiration-Adapted Radiotherapy.

The respiration-adapted radiotherapy is also promising. With this method, the radiation is activated and deactivated with the breathing. In this way, the rays always hit the tumor at the same position. In some cases, the patients are also asked to hold their breath or to breathe in a certain rhythm, which requires training the patients accordingly at the beginning of the treatment. If the anatomical shifts can be purposefully controlled, they can also be purposefully compensated for. This method is also systematically studied at the moment. Here, physicians and physicists mainly calculate how the radiation volume can be decreased by this technique.

Stereotactic radiotherapy takes the place of the scalpel.

Stereotactic radiation, which requires a lot of effort and is so far mostly used for brain tumors, is now also tested by radiotherapists on small tumors of the body stem in especially radiosensitive environments. The exact three-dimensional coordinates of the target area are determined with computer tomograms and a special planning system. To enable a precise transmission of the planned radiation data, the body of the patient is fixated with a frame during the treatment. Under computer-tomographic guidance, markings in this frame are used to direct the radiation precisely at the tumor. In most cases, this is achieved by having the radiation hit the target location from many different directions and at precisely calculated angles.

A team led by Frank Zimmermann from the Klinikum rechts der Isar in Munich presents a study with 68 patients in Leipzig, whose small lung tumors could not be operated on for general health reasons. In 3 to 5 sessions, a high radiation dose was in each case delivered by stereotactic methods. In the so far three-year follow-up period, the tumor resumed its growth in only four patients (6 percent). No serious adverse effects were observed.

Barbara Ritzert | alfa
Further information:
http://www.estro.be

More articles from Health and Medicine:

nachricht Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan

nachricht Prospect for more effective treatment of nerve pain
20.02.2017 | Universität Zürich

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Impacts of mass coral die-off on Indian Ocean reefs revealed

21.02.2017 | Earth Sciences

Novel breast tomosynthesis technique reduces screening recall rate

21.02.2017 | Medical Engineering

Use your Voice – and Smart Homes will “LISTEN”

21.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>