However, so far only 10 to 15 percent of lung cancer patients can be cured permanently. More than half of the patients with a small-cell lung carcinoma and about 65 percent of the patients with a non-small-cell lung carcinoma receive radiation treatment in the course of their illness.
The precision of a three-dimensional radiation planning is, however, limited by nature in the case of lung cancer: During breathing, the tumors shift by a few centimeters. As a consequence, the target area "moves" and can be missed if the radiation limits have been chosen too narrowly. Then the tumor cells will keep growing. But if the radiotherapist chooses the limits of the radiation field too generously, more side effects in the healthy lung are to be expected.
Image guided radiotherapy.
The image guided radiotherapy (IGRT) offers a solution to this dilemma, as experts report at the ESTRO congress in Leipzig. Novel linear accelerators that are equipped with a special x-ray device depict the tumor immediately before the radiation treatment. This allows capturing "moving" target areas. The device registers whether the planned situation matches the real situation. If this is not the case, the computer calculates the deviation, and the radiation table is shifted accordingly.
The respiration-adapted radiotherapy is also promising. With this method, the radiation is activated and deactivated with the breathing. In this way, the rays always hit the tumor at the same position. In some cases, the patients are also asked to hold their breath or to breathe in a certain rhythm, which requires training the patients accordingly at the beginning of the treatment. If the anatomical shifts can be purposefully controlled, they can also be purposefully compensated for. This method is also systematically studied at the moment. Here, physicians and physicists mainly calculate how the radiation volume can be decreased by this technique.
Stereotactic radiotherapy takes the place of the scalpel.
Stereotactic radiation, which requires a lot of effort and is so far mostly used for brain tumors, is now also tested by radiotherapists on small tumors of the body stem in especially radiosensitive environments. The exact three-dimensional coordinates of the target area are determined with computer tomograms and a special planning system. To enable a precise transmission of the planned radiation data, the body of the patient is fixated with a frame during the treatment. Under computer-tomographic guidance, markings in this frame are used to direct the radiation precisely at the tumor. In most cases, this is achieved by having the radiation hit the target location from many different directions and at precisely calculated angles.
A team led by Frank Zimmermann from the Klinikum rechts der Isar in Munich presents a study with 68 patients in Leipzig, whose small lung tumors could not be operated on for general health reasons. In 3 to 5 sessions, a high radiation dose was in each case delivered by stereotactic methods. In the so far three-year follow-up period, the tumor resumed its growth in only four patients (6 percent). No serious adverse effects were observed.
Barbara Ritzert | alfa
Tracking movement of immune cells identifies key first steps in inflammatory arthritis
23.01.2017 | Massachusetts General Hospital
Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign
For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.
According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
23.01.2017 | Health and Medicine
23.01.2017 | Physics and Astronomy
23.01.2017 | Process Engineering