Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Technique to arrest urinary incontinence

29.09.2006
The University Hospital of Navarra is to carry out clinical trials for urinary incontinence using the intraurethral injection of myoblasts (adult stem cells obtained by means of a biopsy of the patient). The trials will be undertaken with 15 women with urinary incontinence.

The project is to recruit the sufferers over a six-month period and to carry out the project jointly between the Cellular Therapy Area and the Department of Urology at the University Hospital of Navarra.

Amongst adult women, incontinence is largely due to the loss of muscular mass of the sphincter, recoverable by injecting this sphincter zone with the patient’s own muscle cells (myoblasts) with the objective of regenerating this muscle, enhancing its contractility and reducing incontinence.

The knowledge of this technique worldwide is confined to less than 200 patients: half a dozen in Canada and about 180 in Austria. The initial idea is the same, although there are differences in how the cells are obtained and in their processing.

Biological scaffolding

The treatment of cystoceles (prolapses of the bladder) is currently undertaken using meshes that act to reinforce the original tissues. These are usually synthetic or of natural (biological) origin, but other, hybrid materials, are being worked with.

Thus, with this collaboration between the Department of Urology and the Cellular Therapy Area in adult stem cell therapy for the treatment of urinary incontinence and prolapses of the pelvic organs, there is another line of research: the use of biological meshes as a support or as “scaffolding” onto which cells are infiltrated so that the myofibroblasts might grow. It is intuitive to believe that the mesh becomes covered with the fibromuscular cells themselves, and that they penetrate the mesh. It is this that is really the reinforcement; the mesh is but a supportive scaffolding rather than an end in itself.

Cooperating in carrying out this project is the BARD company, which manufactures and markets biological meshes. A number of in vitro studies and experiments with animals will be undertaken in order to favour cell growth on the biological meshes and the effect of these with a number of agents. Then they will be implanted in model experimental animals to examine their capacity to integrate into the tissue and carry out the function of support.

Irati Kortabitarte | alfa
Further information:
http://www.elhuyar.com
http://www.basqueresearch.com/berria_irakurri.asp?Gelaxka=1_1&hizk=I&Berri_Kod=1042

More articles from Health and Medicine:

nachricht NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures
17.11.2017 | National Institute of Standards and Technology (NIST)

nachricht High speed video recording precisely measures blood cell velocity
15.11.2017 | ITMO University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

Im Focus: Wrinkles give heat a jolt in pillared graphene

Rice University researchers test 3-D carbon nanostructures' thermal transport abilities

Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

Heavy nitrogen molecules reveal planetary-scale tug-of-war

20.11.2017 | Earth Sciences

Taking a spin on plasma space tornadoes with NASA observations

20.11.2017 | Physics and Astronomy

NASA detects solar flare pulses at Sun and Earth

17.11.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>