Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Fatty liver can cause serious complications says LiU study

It is estimated that fatty liver, steatosis, affects as many as one-fifth of Europe’s adult population. This condition has previously been attributed to alcohol abuse, but is now also associated with excess body weight among those who drink little or no alcohol.

A study conducted at Linköping University (LiU) indicates that the presence of non-alcoholic fatty liver disease (NAFLD) is more serious than previously thought. Affected individuals have a significant risk of developing end-stage liver disease, and the majority may acquire type 2 diabetes which, in turn, can lead to cardiovascular complications.

Details of the study are published in the October 2006 issue of Hepatology, the official journal of the American Association for the Study of Liver Diseases (AASLD). Over a mean period of fourteen years, the LiU research team followed 129 patients who had elevated liver enzymes because of NAFLD. Only 11 subjects (8 %) had been diagnosed with diabetes before entering the study, but when the study population many years later returned for follow-up, 78 percent were found to have the disease or its preliminary stage.

Public health officials will be concerned to learn that the LiU study indicates an increased morbidity among NAFLD patients. “Indeed, these patients run a twofold risk of dying from cardiovascular disease,” says Dr. Stergios Kechagias, chief physician at the Division of Internal Medicine at University Hospital in Linköping, who led the study.

The LiU study also shows that fat in the liver may cause serious liver damage. Microscopic examination of liver tissue samples revealed that 41 percent of the patients had an increasing build-up of scar tissue in the liver. Most at risk were those whose weight gain during the study period exceeded 5 kilo, and those who exhibited the most pronounced accumulation of fat in the liver.

Approximately five percent of the participants developed scar tissue so pronounced that they required hospitalization for cirrhosis-related complications. Half of these patients later developed cancer of the liver.

“Physicians and patients ought to pay more attention to NAFLD, a medical condition that may lead to serious complications. All patients with NAFLD should modify their life-style, starting with exercise and dietary change,” conclude the authors of the Hepatology article: Mattias Ekstedt, Lennart E. Franzén, Ulrik L. Mathiesen, Lars Thorelius, Marika Holmqvist, Göran Bodemar and Stergios Kechagias.

Åke Hjelm | alfa
Further information:

More articles from Health and Medicine:

nachricht Resolving the mystery of preeclampsia
21.10.2016 | Universitätsklinikum Magdeburg

nachricht New potential cancer treatment using microwaves to target deep tumors
12.10.2016 | University of Texas at Arlington

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

Im Focus: Ultra-thin ferroelectric material for next-generation electronics

'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.

Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Resolving the mystery of preeclampsia

21.10.2016 | Health and Medicine

Stanford researchers create new special-purpose computer that may someday save us billions

21.10.2016 | Information Technology

From ancient fossils to future cars

21.10.2016 | Materials Sciences

More VideoLinks >>>