Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Fatty liver can cause serious complications says LiU study

29.09.2006
It is estimated that fatty liver, steatosis, affects as many as one-fifth of Europe’s adult population. This condition has previously been attributed to alcohol abuse, but is now also associated with excess body weight among those who drink little or no alcohol.

A study conducted at Linköping University (LiU) indicates that the presence of non-alcoholic fatty liver disease (NAFLD) is more serious than previously thought. Affected individuals have a significant risk of developing end-stage liver disease, and the majority may acquire type 2 diabetes which, in turn, can lead to cardiovascular complications.

Details of the study are published in the October 2006 issue of Hepatology, the official journal of the American Association for the Study of Liver Diseases (AASLD). Over a mean period of fourteen years, the LiU research team followed 129 patients who had elevated liver enzymes because of NAFLD. Only 11 subjects (8 %) had been diagnosed with diabetes before entering the study, but when the study population many years later returned for follow-up, 78 percent were found to have the disease or its preliminary stage.

Public health officials will be concerned to learn that the LiU study indicates an increased morbidity among NAFLD patients. “Indeed, these patients run a twofold risk of dying from cardiovascular disease,” says Dr. Stergios Kechagias, chief physician at the Division of Internal Medicine at University Hospital in Linköping, who led the study.

The LiU study also shows that fat in the liver may cause serious liver damage. Microscopic examination of liver tissue samples revealed that 41 percent of the patients had an increasing build-up of scar tissue in the liver. Most at risk were those whose weight gain during the study period exceeded 5 kilo, and those who exhibited the most pronounced accumulation of fat in the liver.

Approximately five percent of the participants developed scar tissue so pronounced that they required hospitalization for cirrhosis-related complications. Half of these patients later developed cancer of the liver.

“Physicians and patients ought to pay more attention to NAFLD, a medical condition that may lead to serious complications. All patients with NAFLD should modify their life-style, starting with exercise and dietary change,” conclude the authors of the Hepatology article: Mattias Ekstedt, Lennart E. Franzén, Ulrik L. Mathiesen, Lars Thorelius, Marika Holmqvist, Göran Bodemar and Stergios Kechagias.

Åke Hjelm | alfa
Further information:
http://www.liu.se

More articles from Health and Medicine:

nachricht Penn studies find promise for innovations in liquid biopsies
30.03.2017 | University of Pennsylvania School of Medicine

nachricht 'On-off switch' brings researchers a step closer to potential HIV vaccine
30.03.2017 | University of Nebraska-Lincoln

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Challenging European Research Project to Develop New Tiny Microscopes

The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.

To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

'On-off switch' brings researchers a step closer to potential HIV vaccine

30.03.2017 | Health and Medicine

Penn studies find promise for innovations in liquid biopsies

30.03.2017 | Health and Medicine

An LED-based device for imaging radiation induced skin damage

30.03.2017 | Medical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>