Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Fatty liver can cause serious complications says LiU study

29.09.2006
It is estimated that fatty liver, steatosis, affects as many as one-fifth of Europe’s adult population. This condition has previously been attributed to alcohol abuse, but is now also associated with excess body weight among those who drink little or no alcohol.

A study conducted at Linköping University (LiU) indicates that the presence of non-alcoholic fatty liver disease (NAFLD) is more serious than previously thought. Affected individuals have a significant risk of developing end-stage liver disease, and the majority may acquire type 2 diabetes which, in turn, can lead to cardiovascular complications.

Details of the study are published in the October 2006 issue of Hepatology, the official journal of the American Association for the Study of Liver Diseases (AASLD). Over a mean period of fourteen years, the LiU research team followed 129 patients who had elevated liver enzymes because of NAFLD. Only 11 subjects (8 %) had been diagnosed with diabetes before entering the study, but when the study population many years later returned for follow-up, 78 percent were found to have the disease or its preliminary stage.

Public health officials will be concerned to learn that the LiU study indicates an increased morbidity among NAFLD patients. “Indeed, these patients run a twofold risk of dying from cardiovascular disease,” says Dr. Stergios Kechagias, chief physician at the Division of Internal Medicine at University Hospital in Linköping, who led the study.

The LiU study also shows that fat in the liver may cause serious liver damage. Microscopic examination of liver tissue samples revealed that 41 percent of the patients had an increasing build-up of scar tissue in the liver. Most at risk were those whose weight gain during the study period exceeded 5 kilo, and those who exhibited the most pronounced accumulation of fat in the liver.

Approximately five percent of the participants developed scar tissue so pronounced that they required hospitalization for cirrhosis-related complications. Half of these patients later developed cancer of the liver.

“Physicians and patients ought to pay more attention to NAFLD, a medical condition that may lead to serious complications. All patients with NAFLD should modify their life-style, starting with exercise and dietary change,” conclude the authors of the Hepatology article: Mattias Ekstedt, Lennart E. Franzén, Ulrik L. Mathiesen, Lars Thorelius, Marika Holmqvist, Göran Bodemar and Stergios Kechagias.

Åke Hjelm | alfa
Further information:
http://www.liu.se

More articles from Health and Medicine:

nachricht Correct connections are crucial
26.06.2017 | Charité - Universitätsmedizin Berlin

nachricht One gene closer to regenerative therapy for muscular disorders
01.06.2017 | Cincinnati Children's Hospital Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Predicting eruptions using satellites and math

28.06.2017 | Earth Sciences

Extremely fine measurements of motion in orbiting supermassive black holes

28.06.2017 | Physics and Astronomy

Touch Displays WAY-AX and WAY-DX by WayCon

27.06.2017 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>