Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers find not all drugs are equal in treating teen drivers with ADHD

07.09.2006
Researchers at the University of Virginia Health System have found that teenage drivers with attention deficit hyper activity disorder (ADHD) drive better when they took OROS methylphenidate (OROS MPH), a controlled-release stimulant, rather than extended release amphetamine salts (se-AMPH ER). The findings, which reinforce the use of OROS MPH to improve driving performance in teens with ADHD, will appear in the Sept. issue of Pediatrics.

"Car collisions are two to four times more likely to occur among teens with ADHD. Past studies have shown that stimulants commonly used to treat ADHD can help improve driving performance among this group," said Daniel Cox, Ph.d., lead author and professor of psychiatric medicine at the University of Virginia Health System. "However, there are many different formulations of stimulant drugs to treat ADHD and parents need to know which ones will have the best positive effect."

In previous studies, Cox and his team set out to determine whether immediate-release and extended release drug formulations influence driving performance throughout the day. They found that OROS MPH (Concerta) compared with immediate-release methylphenidate (Ritalin) was better at improving driving performance. The OROS technology uses osmotic pressure to deliver the drug at a controlled rate.

In this study, researchers compared Concerta to se-AMPH ER (Adderall XR). Both are long-acting stimulants used to treat ADHD. Using a driving simulator, teen drivers between 16 and 19 years of age, displayed their driving skills after taking Concerta, Adderall XR or placebo. Study participants took their medications at 8 a.m. They came to the driving simulator laboratory and completed 15-minute simulated drives at 5 p.m., 8 p.m. and 11p.m. Driving performance was determined by sophisticated computer algorithms.

Researchers found that treatments with Concerta led to fewer inattentive driving errors and less hyperactive or impulsive driving errors, such as speeding and inappropriate braking, compared with Adderall XR and placebo.

"This was the first study of its kind to demonstrate that OROS methylphenidate has therapeutic benefits among teens for up to 15 hours," said Cox. "We hope these results encourage teens to be vigilant in taking their medication as prescribed to help contribute to their driving safety and help them appreciate the benefits of stimulant therapy."

"The study suggests that Concerta should be the initial treatment of choice for teen drivers with ADHD, though teens already on Adderall XR should not necessarily switch medications if they demonstrate a robust therapeutic response", according to Cox.

In addition, accidents occur most frequently in the evenings and on weekends, meaning parents should not necessarily limit medication use to school days.

Abena Foreman-Trice | EurekAlert!
Further information:
http://www.virginia.edu

More articles from Health and Medicine:

nachricht Organ-on-a-chip mimics heart's biomechanical properties
23.02.2017 | Vanderbilt University

nachricht Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Stingless bees have their nests protected by soldiers

24.02.2017 | Life Sciences

New risk factors for anxiety disorders

24.02.2017 | Life Sciences

MWC 2017: 5G Capital Berlin

24.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>