Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers find not all drugs are equal in treating teen drivers with ADHD

07.09.2006
Researchers at the University of Virginia Health System have found that teenage drivers with attention deficit hyper activity disorder (ADHD) drive better when they took OROS methylphenidate (OROS MPH), a controlled-release stimulant, rather than extended release amphetamine salts (se-AMPH ER). The findings, which reinforce the use of OROS MPH to improve driving performance in teens with ADHD, will appear in the Sept. issue of Pediatrics.

"Car collisions are two to four times more likely to occur among teens with ADHD. Past studies have shown that stimulants commonly used to treat ADHD can help improve driving performance among this group," said Daniel Cox, Ph.d., lead author and professor of psychiatric medicine at the University of Virginia Health System. "However, there are many different formulations of stimulant drugs to treat ADHD and parents need to know which ones will have the best positive effect."

In previous studies, Cox and his team set out to determine whether immediate-release and extended release drug formulations influence driving performance throughout the day. They found that OROS MPH (Concerta) compared with immediate-release methylphenidate (Ritalin) was better at improving driving performance. The OROS technology uses osmotic pressure to deliver the drug at a controlled rate.

In this study, researchers compared Concerta to se-AMPH ER (Adderall XR). Both are long-acting stimulants used to treat ADHD. Using a driving simulator, teen drivers between 16 and 19 years of age, displayed their driving skills after taking Concerta, Adderall XR or placebo. Study participants took their medications at 8 a.m. They came to the driving simulator laboratory and completed 15-minute simulated drives at 5 p.m., 8 p.m. and 11p.m. Driving performance was determined by sophisticated computer algorithms.

Researchers found that treatments with Concerta led to fewer inattentive driving errors and less hyperactive or impulsive driving errors, such as speeding and inappropriate braking, compared with Adderall XR and placebo.

"This was the first study of its kind to demonstrate that OROS methylphenidate has therapeutic benefits among teens for up to 15 hours," said Cox. "We hope these results encourage teens to be vigilant in taking their medication as prescribed to help contribute to their driving safety and help them appreciate the benefits of stimulant therapy."

"The study suggests that Concerta should be the initial treatment of choice for teen drivers with ADHD, though teens already on Adderall XR should not necessarily switch medications if they demonstrate a robust therapeutic response", according to Cox.

In addition, accidents occur most frequently in the evenings and on weekends, meaning parents should not necessarily limit medication use to school days.

Abena Foreman-Trice | EurekAlert!
Further information:
http://www.virginia.edu

More articles from Health and Medicine:

nachricht Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin

nachricht Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

How herpesviruses win the footrace against the immune system

26.05.2017 | Life Sciences

Water forms 'spine of hydration' around DNA, group finds

26.05.2017 | Life Sciences

First Juno science results supported by University of Leicester's Jupiter 'forecast'

26.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>