Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Hirsute-s you, Sir! Could super furry animals provide clues for baldness?

29.08.2006
Scientists looking at mice may have discovered why certain people are hairier than others in what could provide clues as to the reason some men go bald prematurely.

The University of Manchester team has laid bare the molecular processes that determine which embryonic skin cells will form into hair follicles and determine the body's hair pattern.

The findings will be of interest to scientists looking at male-pattern baldness but have more direct implications for people who suffer from ectodermal dysplasia - a range of conditions where skin cells fail to develop into other tissue, including hair follicles.

“During human development, skin cells have the ability to turn into other types of cells to form hair follicles, sweat glands, teeth and nails,” said Dr Denis Headon, who led the research. “Which cells are transformed into hair follicles is determined by three proteins that are produced by our genes.

“Our research has identified how one of these proteins working outside of the cell interacts at a molecular level to determine an individual's hair pattern as the embryonic skin spatially organises itself.”

The team found that cells given the genetic command to become hair follicles will send out signals to neighbouring cells to prevent them from doing likewise, so producing a specific hair pattern. They also demonstrated that by hyperactivating the `hair protein' in embryonic mice, young with considerably more fur than normal were produced.

“We were able to change the number of hair follicles in the embryonic mice while they were developing in the womb,” said Dr Headon, who is based in the University's Faculty of Life Sciences.

“The findings could have implications for sufferers of ectodermal dysplasia that are missing this particular protein and who are unable to develop hair follicles during embryonic development.

“The research - while not directly linked to male-pattern baldness - should be of interest to pharmaceutical companies working in this field as understanding the molecular processes at work during follicle development could provide clues as to why follicles shrink and hair growth diminishes in certain men as they get older.”

Aeron Haworth | alfa
Further information:
http://www.manchester.ac.uk

More articles from Health and Medicine:

nachricht TSRI researchers develop new method to 'fingerprint' HIV
29.03.2017 | Scripps Research Institute

nachricht Periodic ventilation keeps more pollen out than tilted-open windows
29.03.2017 | Technische Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Challenging European Research Project to Develop New Tiny Microscopes

The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.

To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Researchers shoot for success with simulations of laser pulse-material interactions

29.03.2017 | Materials Sciences

Igniting a solar flare in the corona with lower-atmosphere kindling

29.03.2017 | Physics and Astronomy

As sea level rises, much of Honolulu and Waikiki vulnerable to groundwater inundation

29.03.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>